Developmental, behavioral and endocrine alterations in male rats at early and late postnatal life following in utero exposure to low dose di--butylphthalate.

Environmental chemical pollutants that interfere with hormonal homeostasis or hormone signaling are the relevant agents inducing congenital or postnatally developed reproductive abnormalities in human beings, wild and domestic animals. In this study, we are examining reproductive effects of prenatal exposure of male rats to a low dose di--butylphthalate (DBP). Wistar female rats were given intragastrically DBP at a daily dose of 100 mg/kg b.