Digital mental health interventions for the treatment of depression: A multiverse meta-analysis.

Background: The varying sizes of effects in published meta-analyses on digital interventions for depression prompt questions about their efficacy.

Methods: A systematic search in Embase, PsycINFO, and PubMed identified 125 randomised controlled trials up to February 2023, comparing digital interventions for depression against inactive controls. The stability of results was evaluated with a multiverse meta-analysis, thousands of meta-analyses were conducted based on different combinations of analytical choices, like target populations, intervention characteristics, and study designs.

The effectiveness of self-guided interventions in adults with depressive symptoms: a systematic review and meta-analysis.

Background: Despite promising scalability and accessibility, evidence on the efficacy of self-guided interventions for adult depression is inconclusive. This study investigated their effectiveness and acceptability, considering diverse delivery formats and support levels.

Methods: We systematically searched PubMed, PsycINFO, Embase, and Cochrane Library until 1st January 2024.

Psychotherapy for adult depression in low- and middle-income countries: an updated systematic review and meta-analysis.

Previous meta-analyses on psychotherapy for adult depression have found a larger treatment effect in non-Western trials compared to Western trials (i.e. North America, Europe, and Australia).