Outcome and prognosis of pediatric patients with delayed diagnosis of open-globe injuries.

Purpose: Open-globe injuries in children can present in a delayed fashion, potentially increasing the risk of endophthalmitis and delaying surgical intervention. This article presents the outcome of pediatric patients with delayed diagnosis of open-globe injuries for 24 hours or more.

Methods: The study was a retrospective observational case series of patients who presented with open-globe injuries diagnosed 24 hours or more after the injury between July 2002 and March 2007.

Association between thyroid-stimulating immunoglobulin levels and ocular findings in pediatric patients with Graves disease.

Purpose: Graves ophthalmopathy and Graves disease may be caused by the same autoimmune process. An explanation for this may be the presence of autoantibodies reacting with an autoantigen in the orbit and the thyroid gland, like the thyroid-stimulating hormone (TSH) receptor. The purpose of this study was to see if initial levels of TSH receptor antibodies, known as thyroid-stimulating immunoglobulin (TSI), in pediatric patients with Graves disease were associated with the development of Graves ophthalmopathy during the follow-up period.