Publications by authors named "Olga L Bulgakova"
Int J Mol Sci
December 2023
Article Synopsis
- Type 2 diabetes mellitus (T2D) is a chronic condition marked by insulin resistance and dysfunction of β-cells, leading to various health complications.
- A study analyzed plasma samples from 44 T2D patients and 22 healthy individuals, revealing 229 miRNAs with significant expression differences, including increased levels of miR-5588-5p and decreased levels of miR-496 in T2D patients.
- The researchers also found that obesity affects miRNA expression, specifically miR-144-3p and miR-99a-5p, and identified key pathways related to chromatin modification and apoptosis linked to certain miRNAs.
