Erratum to: 'Normal endothelial but impaired arterial development in MAP-Kinase activated protein kinase 2 (MK2) deficient mice'.

[This corrects the article DOI: 10.1186/s13221-016-0038-2.].

Normal endothelial but impaired arterial development in MAP-Kinase activated protein kinase 2 (MK2) deficient mice.

Angiogenesis is a fundamental process during development and disease, and many details of the underlying molecular and cellular mechanisms are incompletely understood. Mitogen-activated protein kinase (MAPK)-activated protein kinase 2 (MK2), a major downstream target of p38 MAPK, has recently been identified as a regulator of Interleukin 1β dependent angiogenesis in vivo, and in vitro data suggest a role of MK2 for VEGF-dependent angiogenic processes in endothelial cells. We thus hypothesized that MK2 plays a role during physiological vascular development in vivo.

Vascular importance of the miR-212/132 cluster.

Rationale: Many processes in endothelial cells including angiogenic responses are regulated by microRNAs. However, there is limited information available about their complex cross-talk in regulating certain endothelial functions.

Aim: The objective of this study is to identify endothelial functions of the pro-hypertrophic miR-212/132 cluster and its cross-talk with other microRNAs during development and disease.