Publications by authors named "Olga Doroshenko"

Article Synopsis
  • The study aims to improve the diagnosis and treatment of congenital heart diseases by examining the relationship between hemodynamic parameters and the structure of the thoracic aorta.
  • Researchers utilized multi-slice spiral CT images of the aorta from patients with and without heart issues to create numerical models and estimate hemodynamic features using fluid dynamics techniques.
  • A metamodel was developed that accurately classifies different aorta types, indicating that structural measurements can reliably predict hemodynamic characteristics, and this approach can be applied to other heart conditions as well.
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Cohesive and adhesive bindings degrade during operation and maintenance even if contacting materials in a manufactured laminated structure are perfectly matched at the interfaces. Two modelling approaches for describing partially closed delaminations or imperfect contact zones, which often occurs at the interfaces, are examined and considered. To confirm the adequateness of the applicability of the effective spring boundary conditions for guided wave scattering by a finite length delamination, guided wave propagation through a damaged zone with a distribution of micro-cracks is compared with an equivalent cohesive zone model, where the spring stiffnesses for the effective boundary conditions are calculated using the properties of the considered crack distribution.

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This paper was originally published under standard Springer Nature copyright. As of the date of this correction, the Analysis is available online as an open-access paper with a CC-BY license. No other part of the paper has been changed.

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Single-molecule Förster resonance energy transfer (smFRET) is increasingly being used to determine distances, structures, and dynamics of biomolecules in vitro and in vivo. However, generalized protocols and FRET standards to ensure the reproducibility and accuracy of measurements of FRET efficiencies are currently lacking. Here we report the results of a comparative blind study in which 20 labs determined the FRET efficiencies (E) of several dye-labeled DNA duplexes.

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The dynamic architecture of chromatin fibers, a key determinant of genome regulation, is poorly understood. Here, we employ multimodal single-molecule Förster resonance energy transfer studies to reveal structural states and their interconversion kinetics in chromatin fibers. We show that nucleosomes engage in short-lived (micro- to milliseconds) stacking interactions with one of their neighbors.

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