Publications by authors named "Olga A Solovova"
Article Synopsis
- - Male infertility, particularly linked to poor semen quality, is found in roughly 50% of infertile couples, with specific CFTR gene variants being common causes of azoospermia.
- - This study analyzed the allele frequency of 12 CFTR variants in fertile and infertile men across different regions of Russia, using data from a CF patient registry and local biocollections.
- - Findings revealed significant regional differences in CFTR variant frequencies, confirming that certain variants like F508del and CFTRdele2,3(21kb) are more prevalent in infertile patients compared to healthy individuals, highlighting the need for genetic monitoring in Russian populations.
Various pathogenic factors can lead to oogenesis failure and seriously affect both female reproductive health and fertility. Genetic factors play an important role in folliculogenesis and oocyte maturation but still need to be clarified. Oocyte maturation is a well-organized complex process, regulated by a large number of genes.
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