Effect of C Fullerene on Muscle Injury-Induced Rhabdomyolysis and Associated Acute Renal Failure.

Introduction: Rhabdomyolysis, as an acute stage of myopathy, causes kidney damage. It is known that this pathology is caused by the accumulation of muscle breakdown products and is associated with oxidative stress. Therefore, the present study evaluated the effect of intraperitoneal administration (dose 1 mg/kg) of water-soluble C fullerenes, as powerful antioxidants, on the development of rat kidney damage due to rhabdomyolysis caused by mechanical trauma of the of different severity (crush syndrome lasting 1 min under a pressure of 2.