The activities of the key antioxidant enzymes superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GP) and glutathione reductase (GR) as well as levels of reduced glutathione (GSH) and integral antioxidant activity (IAA), were studied in the digestive glands and gills of 14 bivalve species. Species and tissue differences of the antioxidant (AO) systems of the investigated mollusks were discussed in connection with their physiological and biochemical peculiarities. This article describes the role of the AO system of mollusks in adaptation to natural habitat conditions and shows the relationship of AO activity with the maximum habitat depth (MHD) and maximum lifespan (MLS) of these species.
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