Publications by authors named "Olena Pankova"
Article Synopsis
- The study assessed plasma relaxin-2 (RLN-2) levels in 106 patients with arterial hypertension (AH) and compared them to 30 healthy controls.
- Results indicated that RLN-2 levels were significantly lower in hypertensive patients, especially those with type 2 diabetes (T2DM), and were negatively correlated with blood pressure, body measurements, and various metabolic parameters.
- The findings suggest that decreased RLN-2 levels could serve as a potential biomarker for diagnosing AH in patients with T2DM, highlighting its association with glucose metabolism and lipid profiles.
Catestatin (CST) is a pleiotropic peptide with cardioprotective and metabolic effects. CST is involved in the pathogenesis of both arterial hypertension (AH) and type 2 diabetes mellitus (T2DM), which are the risk factors of cardiovascular diseases. In this study, we aimed to investigate the plasma CST levels in hypertensive patients, especially with T2DM, as well as compare those with healthy volunteers, and explore the relationship between CST levels and clinical, anthropometric and laboratory parameters.
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