Integrated In Vivo and In Vitro Evaluation of a Powder-to-Hydrogel, Film-Forming Polymer Complex Base with Tissue-Protective and Microbiome-Supportive Properties.

The study aimed to perform a comprehensive in vitro and in vivo evaluation of a newly developed, patent-pending, powder-to-hydrogel, film-forming polymer complex base, which possesses tissue-protective and microbiome-supportive properties, and to compare its characteristics with poloxamer 407. The study used a combination of in vitro assays, including tissue viability and cell migration, and in vivo wound healing evaluations in male diabetic mice. Microbiome dynamics at wound sites were also analyzed.

Analysis of the Physical Characteristics of an Anhydrous Vehicle for Compounded Pediatric Oral Liquids.

The paucity of suitable drug formulations for pediatric patients generates a need for customized, compounded medications. This research study was set out to comprehensively analyze the physical properties of the new, proprietary anhydrous oral vehicle SuspendIt Anhydrous, which was designed for compounding pediatric oral liquids. A wide range of tests was used, including sedimentation volume, viscosity, droplet size after dispersion in simulated gastric fluid, microscopic examination and content uniformity measurements to evaluate the properties of the anhydrous vehicle.

Realities of Pharmaceutical Compounding in the Republic of Uzbekistan.

The development of compounding science in the Republic of Uzbekistan began in ancient times. The emergence of medical science on the territory of modern Uzbekistan was associated with the activities of the famous physician Ibn Sina (Avicenna). His Canon of Medicine is still considered the main source of medical knowledge in the world.

Authentication of , and liquid extract from the Ukrainian market using HPTLC chromatographic profiles.

and are widely distributed and sold in Eastern Europe. The purpose of this paper was to identify , and liquid extract (RRLE) in the Ukrainian market and bring out adulteration cases using chromatographic characterisation by HPTLC. The multiple samples of , and RRLE were compared; the optimal chromatographic conditions for identification of and RRLE based on the presence of rosavins and salidroside as well as for identification of based on the presence of salidroside were proposed; the specific HPTLC fingerprints were obtained; the acceptance criteria for each product were set.

Chromatographic characterization on flavonoids and triterpenes of leaves and flowers of 15 L. species.

The Hawthorn ( L.) is the most commonly used herb for treating cardiovascular diseases. The purpose of this paper was the analysis and comparison of HPTLC chromatographic profiles of flavonoids and triterpenes of leaves and flowers of 15 L.

Investigation of the Physical, Chemical, and Microbiological Stability of Oral Solutions Compounded with Herbals.

The physical, chemical, and microbiological stability of a compounded oral solution with the active ingredients herbal tinctures of valerian and motherwort with sedative action for pediatric treatment was studied. Evaluations for physical, chemical, and microbiological stability were performed initially and throughout the storage period. Physical stability of the oral solution was assessed by coloration, clarity, and pH of the solution.

Compounding in Nigeria.

Although the art of apothecary existed as early as the first settlers in the location known today as Nigeria, the practice of pharmacy has transformed from training of dispensers in the 17th century to compounding pharmacists. Compounding, currently carried out exclusively in hospital pharmacies in Nigeria, is a relatively small but significant part of pharmaceutical care since it is tailored to individual/ special patients for positive therapeutic outcomes. This aspect of pharmaceutical service suffers challenges in Nigeria.

Investigation of physical and chemical stability of ointment with herbals.

The physical and chemical stability of a stock preparation ointment with active ingredients-herbal tinctures of calendula and arnica-for the treatment of hemorrhoids was studied. Evaluations for physical and chemical stability were performed initially and throughout the storage period. Physical stability of the ointment was assessed by means of visual observation in normal room light.

Compounding in Ukraine.

Pharmaceutical compounding in modern Ukraine has a rich history and goes back to ancient times. Today in the Ukraine, there is a revival of compounding practice, the opening of private compounding pharmacies, updating of legislative framework and requirements of the State Pharmacopeia of Ukraine for compounding preparations, and the introduction of Good Pharmaceutical Practice.