Publications by authors named "Oleg Zhuk"
Article Synopsis
- * A study analyzed 34,128 COVID-19 patients across the US, South Korea, and Spain, revealing differences in gender and age demographics among countries.
- * Compared to influenza patients hospitalized from 2014-2019, COVID-19 patients tend to be younger, more often male, and have fewer comorbidities and lower medication use, indicating a need for tailored response strategies.
Article Synopsis
- The study investigated the safety of hydroxychloroquine, a drug used for rheumatoid arthritis, particularly considering its controversial use for COVID-19 pneumonia.
- It compared adverse events in patients starting hydroxychloroquine versus those starting sulfasalazine, analyzing data from multiple countries and focusing on severe events within a 30-day period.
- Results showed no significant increase in severe adverse events for short-term use of hydroxychloroquine compared to sulfasalazine, but long-term use may be linked to a higher risk of cardiovascular issues.
Background In this study we phenotyped individuals hospitalised with coronavirus disease 2019 (COVID-19) in depth, summarising entire medical histories, including medications, as captured in routinely collected data drawn from databases across three continents. We then compared individuals hospitalised with COVID-19 to those previously hospitalised with influenza. Methods We report demographics, previously recorded conditions and medication use of patients hospitalised with COVID-19 in the US (Columbia University Irving Medical Center [CUIMC], Premier Healthcare Database [PHD], UCHealth System Health Data Compass Database [UC HDC], and the Department of Veterans Affairs [VA OMOP]), in South Korea (Health Insurance Review & Assessment [HIRA]), and Spain (The Information System for Research in Primary Care [SIDIAP] and HM Hospitales [HM]).
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