Publications by authors named "Oleg V Zayratyants"
Recent studies indicate that cilia impairment, accompanied by the axonema loss and the basal body misorientation, is a common pathological feature of SARS-CoV-2-infected bronchial epithelial cells. However, these data were obtained using either cultured cells, or animal models, while in human postmortem material, cilia impairment has not been described yet. Here, we present direct observation of cilia impairment in SARS-CoV-2-infected bronchial epithelial cells using transmission electron microscopy of the autopsy material.
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- - Pneumonia, particularly during the COVID-19 pandemic, has been linked to abnormal lipid depositions in the lungs, observed in both COVID-19 and other pneumonia cases.
- - Analysis of lung specimens showed that these lipid deposits were found near inflamed regions and could disrupt blood flow, with characteristics that remained consistent across different types of pneumonia.
- - The study indicates that altered lipid metabolism in lung tissue and changes in fatty acid content offer potential new targets for pneumonia treatments, regardless of the underlying cause.
Corneal Stroma Regeneration with Collagen-Based Hydrogel as an Artificial Stroma Equivalent: A Comprehensive In Vivo Study.
Polymers (Basel)
September 2022
Restoring the anatomical and functional characteristics of the cornea using various biomaterials is especially relevant in the context of a global shortage of donor tissue. Such biomaterials must be biocompatible, strong, and transparent. Here, we report a Viscoll collagen membrane with mechanical and optical properties suitable for replacing damaged stromal tissue.
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