Publications by authors named "Oleg Tcholakov"

A 5-year-old boy sustained blunt abdominal trauma in a car crash. The buckle mechanism of the five-point harness of his child safety seat compressed his upper abdomen causing an isolated complete pancreatic rupture. Diagnosis was delayed due to subtle symptoms and normal initial findings.

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Background: Intraoperative Doppler ultrasonography is a non-invasive method with a great potential for the assessment of perfusion in surgery. This study aimed to determine the accuracy of Doppler ultrasonography in the assessment of blood flow on the top of an Akiyama-fashioned stomach tube for esophagus substitution. A secondary point of interest was the real length gained after construction of the gastric tube.

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Article Synopsis
  • Antibiotic treatment is crucial for managing severe acute pancreatitis, and the study focuses on how well cefepime penetrates pancreatic tissue in two acute pancreatitis models.
  • After inducing pancreatitis in animals and administering cefepime, the concentration of the drug in pancreatic tissue was significantly higher in both mild and severe cases compared to control animals.
  • The study concludes that cefepime maintains effective levels in pancreatic tissue over time and significantly reduces infection rates, suggesting its potential for treating severe acute pancreatitis in patients.
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