The temporary impact of COVID-19 on semen deoxyribonucleic acid fragmentation.

Introduction: Coronavirus disease 2019 (COVID-19) is characterized by impact on different systems of human body. Recently, several anti-COVID vaccines have been developed.

Material And Methods: In our study, we included two groups of males: GROUP1, anti-COVID vaccinated males, n = 46, and GROUP2, n = 43, non-vaccinated males, who all fell ill with the Coronavirus infection.

Efficacy of combination therapy tadalafil plus tamsulosin in ureteral stents-related symptoms relief.

Introduction: Ureteral stents-related symptoms (USRs) are the common complications of ureteral stenting. Tamsulosin a selective alpha-1 blocker and Tadalafil a PDE-5 inhibitor are one of drugs have been used for USRs relief. In this study we aimed to evaluate the effectiveness and safety of combination therapy Tamsulosin+Tadalafil for treating USRs comparing it with the efficacy of either Tamsulosin or Tadalafil monotherapies.

Mixed Sexually Transmitted Infections in Infertile Couples: Empirical Treatment and Influence on Semen Quality.

Background: Trichomonas vaginalis (TV), Mycoplasma genitalium (MG) and Ureaplasma urealyticum (UU) are common sexually transmitted infections (STIs) that are diagnosed in infertile couples (cps). In cases with their simultaneous presence in a patient (mixed STI, MSTIs), treatment is complicated by the different sensitivity of microorganisms to antibacterial drugs. Moreover, in cases of complicated infections, the empirical treatment should be started before obtaining the results of drug susceptibilities.

Assessment of the effectiveness of radiofrequency ablation as a technique for destroying small renal tumors in patients older than 70.

Introduction: During the past few decades, the percentage of older people in the population has been steadily growing due to the tendency of extended life expectancy. The efficacy of radiofrequency ablation (RFA) and tumor enucleoresection (TE) in the treatment of selected older patients with renal cell carcinoma (RCC) T1aN0M0 sized ≤4.0 cm has been a popular topic in many recent studies.

Acute epididymo-orchitis: relevance of local classification and partner's follow-up.

Introduction: Acute epididymo-orchitis (AEO) is a male urological emergency without an approved clinical classification. We aimed to determine the clinical value of proposed in 2012 local AEO classification system and summarize results of partner's follow-up.

Material And Methods: A total of 293 patients with AEO were enrolled into our study.

Empirical treatment in patients with acute obstructive pyelonephritis.

Acute obstructive pyelonephritis (AOP) is a urological life-threatening inflammatory condition that initially requires immediate urinary drainage and simultaneous prescribing of highly effective targeted antibacterial treatment. The empirical antibacterial therapy is always prescribed before urine culture and susceptibility testing are done. Percutaneous nephrostomy (PNS) and ureteral stenting (US) are the two options for urinary drainage in obstructed kidneys, while fluoroquinolones and 3(rd) generation cephalosporins are the main groups of antibacterial drugs that are recommended and are available for empirical AOP therapy.

The influence of direct mobile phone radiation on sperm quality.

Introduction: It is impossible to imagine a modern socially-active man who does not use mobile devices and/or computers with Wi-Fi function. The effect of mobile phone radiation on male fertility is the subject of recent interest and investigations. The aim of this study was to investigate the direct in vitro influence of mobile phone radiation on sperm DNA fragmentation and motility parameters in healthy subjects with normozoospermia.

Renal cell carcinoma: how to hit the targets?

Introduction: Renal cell carcinoma (RCC) is a widespread oncourological disease with a tendency towards a slow increase of incidence. In the recent decade, there has been development of numerous effective drugs targeted at different molecules that play a dominant role in RCC carcinogenesis. Understanding of RCC carcinogenesis confirms the key role of angiogenesis in maintaining the viability of renal tumours and their metastases.

Strangulation of the penis: two case reports.

Till now numerous reports have depicted the different constricting devices (CDs) previously threaded on the penis for obtaining of sexual pleasure or/and prolonged erection. The causes of CD bearing on the penis are sexual or autoerotic actions. Here we present two cases of successful removal of a metal device from a penis that was associated with trauma grade II according to Bhat et al.

Mental status in patients with chronic bacterial prostatitis.

Introduction: Chronic prostatitis is a widespread urological disease with a lengthy course and a propensity to frequent recurrences. Adequate response to anti-inflammatory therapy is lacking in a high percentage of patients, which causes them to seek medical advice from different doctors. Thus, the physicians are challenged to look for other reasons causing the pathological symptoms.

Acute epididymo-orchitis: staging and treatment.

Introduction: Acute epididymo-orchitis (AEO) is an acute inflammatory disease of the epididymis and ipsilateral testis. Treatment should be started immediately after diagnosis and includes antibiotics, analgesics, and, if necessary, surgery.

Materials And Methods: After AEO diagnosis, patients were treated conservatively with analgesics and antibiotics.

Radical or simple nephrectomy in localized renal cell carcinoma: what is a choice?

Introduction: Renal cell carcinoma (RCC) accounts for approximately 3% of all adult malignancies. Surgery remains the only effective method of renal tumors treatment. In fact, for advanced RCC, radical nephrectomy (RN) should remain a standard treatment.