Dimethyl sulfoxide (DMSO), a by-product of the pulping industry, is widely used in biological research, cryobiology and medicine. On cellular level DMSO was shown to suppress NMDA-AMPA channels activation, blocks Na+ channel activation and attenuates Ca2+ influx (Lu and Mattson 2001). In the present study we explored the whole-cell patch-clamp to examine the acute effect of high concentrations of DMSO (0.
View Article and Find Full Text PDFAbstract Effects of stem and progenitor cells or their compounds on recipient cells are investigated intensively today. In spite of this, their ability to interact with native cells and the final targets affected by them, particularly biochemical parameters that characterize cell redox-dependent processes, remain little studied. We have studied how bioregulators of stem and progenitor cells affect these processes in freshly isolated liver after animal pretreatment in vivo.
View Article and Find Full Text PDFThe influence of the follicle size, rapid freezing to -196 degrees capital ES, Cyrillic and cryopreservation in liquid nitrogen within a period of one month of the human ovary follicular fluid (FF) on its dielectric properties is studied by the microwave dielectric method. The FF was obtained from dominant follicles of patients who received treatment for infertility by extracorporal fertilization. We have measured the real part (epsilon') of the complex permittivity of the native and frozen follicular fluids at the room temperature.
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