Efficacy of a web-based healthcare innovation to advance the quality of life and care of patients with an implantable cardioverter defibrillator (ACQUIRE-ICD): a randomized controlled trial.

Aims: Modern clinical management of patients with an implantable cardioverter defibrillator (ICD) largely consists of remote device monitoring, although a subset is at risk of mental health issues post-implantation. We compared a 12-month web-based intervention consisting of goal setting, monitoring of patients' mental health-with a psychological intervention if needed-psychoeducational support from a nurse, and an online patient forum, with usual care on participants' device acceptance 12 months after implantation.

Methods And Results: This national, multi-site, two-arm, non-blinded, randomized, controlled, superiority trial enrolled 478 first-time ICD recipients from all 6 implantation centres in Denmark.

High level of post-traumatic stress symptoms in patients with chronic neck pain is associated with poor mental health but does not moderate the outcome of a multimodal physiotherapy programme.

Introduction: Chronic traumatic neck pain has a high prevalence of post-traumatic stress symptoms (PTSS). However, whether PTSS moderates treatment effects is unknown. This study investigated: 1) whether PTSS was associated with patient-reported outcomes and clinical test results at baseline; 2) whether PTSS moderated the effect of a multimodal physiotherapy intervention of exercise therapy and patient education; and 3) whether adherence to the intervention differed across PTSS groups.

Anxiety and depression as risk factors for ICD shocks and mortality in patients with an implantable cardioverter defibrillator - A systematic review.

Objective: To examine associations between baseline anxiety and depression and occurrence of ICD shocks and risk of mortality in patients with an implantable cardioverter defibrillator (ICD).

Method: We systematically searched EMBASE, PubMed, PsycINFO, and CINAHL for eligible studies fulfilling the predefined criteria.

Results: We included 37 studies based on 25 different cohorts following 35,003 participants for up to seven years.

Relevance versus big numbers: Students' criteria for selecting scholarly references online.

This study examined the effect of the number of citations attributed to documents on third year psychology students' selection of bibliographical references. Our main assumption was that students would take high numbers of citations as accessible relevance cues and use them heuristically to facilitate decision making, potentially bypassing deeper relevance assessment based on semantic processing. Experiment 1 presented the students with a reference selection task while manipulating the number of citations attributed to references, and found that the number of citations had a strong impact on reference selection.

Psychological distress in patients with an implantable cardioverter defibrillator and their partners.

Objectives: Adjustment to life with an implantable cardioverter defibrillator (ICD) may be challenging for some patients and their partners, with disease and individual characteristics likely influencing the process. We examined whether perceived social support and clinical patient characteristics are associated with change in couples' symptoms of anxiety and depression in the first year after ICD implantation, and explored whether the associations differ between patients and partners.

Method: A cohort of consecutively implanted patients (n = 286; 21% women) and their partners completed questionnaires on social support and symptoms of anxiety and depression prior to ICD implantation and 12 months later.

Microdialysis as a tool to determine the local tissue concentration of dicloxacillin in man.

Aims: The most common pathogen to cause postoperative infections in Denmark is Staphylococcus aureus. Despite using prophylactic antibiotics, infections are still seen. Whether the tissue concentration is above the minimal inhibitory concentration (MIC) for the pathogen is unknown.

Follow-up after initial surgical treatment of soft tissue sarcomas in the extremities and trunk wall.

Background/objectives: Evaluation of our surveillance program for soft tissue sarcomas (STS) and borderline tumors (BT) for identification of local recurrence and lung metastases the first 2 years postoperatively.

Methods: We retrospectively assessed the medical files of all patients (n = 232) with STS and BT of the extremities and trunk wall who underwent surgery from 2010 to 2013. Two-hundred-and-thirty-two patients were included in the local recurrence study and 116 patients in the lung metastasis study.

Study Design and Cohort Description of DEFIB-WOMEN: A National Danish Study in Patients with an ICD.

Background: Little systematic evidence is available on potential gender differences in patients with an implantable cardioverter defibrillator (ICD) from a real-world cohort. We designed the DEFIB-WOMEN (The Utilization of Implantable Cardioverter DEFIBrillator Therapy in the Treatment of Heart Disease: Clinical and Psychological outcomes in WOMEN) study to examine gender differences on (1) patient-reported outcomes (PROs), (2) procedure- and device-related complications, and (3) ventricular tachyarrhythmia and mortality. This presents the study design and baseline characteristics of the cohort.

Complications and functional outcome after fixation of distal tibia fractures with locking plate - A multicentre study.

Introduction: The aim of this study was to evaluate the proportion of complications and the functional outcome following ORIF with low-profile locking plates in patients with distal tibia fractures.

Method: Retrospective data was retrieved using county databases, operation books, health record and X-ray images for 6 hospitals (1 level 1, 5 level 2) in the Region of Southern Denmark. Between January 2007 and April 2011 70 consecutive patients with 71 distal tibia fractures were treated with low-profile locking plate were included.

Reconstruction of a complicated adjacent non-union of the radius and ulna using a free vascularised double-barrel fibula graft.

While the free vascularised double-barrel fibula flap has been traditionally used in the reconstruction of defects in the long bones of the lower extremities, the advantages of this type of graft can also be seen in the treatment of adjacent radial and ulnar non-unions of the forearm. The main advantage of the double-barrel fibula flap in treatment of antebrachial non-unions is that it allows for the simultaneous anatomical reconstruction of the radius and the ulna while maximising forearm functionality. In contrast to other procedures, this tailored graft also helps preserve pronation and supination of the forearm.

Substantial reduction in the number of amputations among patients with diabetes: a cohort study over 16 years.

Aims/hypothesis: The aim of this study was to describe the trends in rates of amputation among individuals with and without diabetes.

Methods: We studied amputation rates in the County of Funen (approximately 0.5 million residents) during the period 1996-2011.

[Radiation therapy for heterotopic ossification prophylaxis].

Heterotopic ossification (HO) is a well-known condition of bone formation in soft tissues due to trauma (e.g. surgery) or neurological injury, but the exact aetiology is unknown.

Newly diagnosed type 1 diabetes complicated by ketoacidosis and peripheral thrombosis leading to transfemoral amputation.

Peripheral vascular thromboembolism is a rarely described complication of diabetic ketoacidosis. We report a 41-year-old otherwise healthy man admitted with ketoacidosis and ischaemia of the left foot. The patient was unsuccessfully treated with thromboendarterectomy, and the extremity was ultimately amputated.

[Peroneal nerve palsy in patient with Ehlers-Danlos syndrome].

Ehlers-Danlos syndrome (EDS) is a hereditary generalized connective tissue disorder characterized by skin hyperextensibility, joint hypermobility and tissue fragility. Peripheral neuropathy is described sporadically. Although the exact mechanism of the neuropathy is not well-known, excessive stretch and abnormal connective tissue support are the suggested causative agents.

[Neonate with congenital solitary eosinophilic granuloma in the forearm].

Localized Langerhans cell histiocytosis, also known as eosinophilic granuloma (EG), is a benign tumour-like inflammatory disease with variable clinical course. The peak incidence of EG is between five and ten years of age. EG in children down to the age of two years has been described.

Pyoderma gangraenosum as a complication to knee arthroscopy.

Pyoderma gangraenosum (PG) is a rare immunologic ulcerative disease, which sometimes develop as a complication to surgery. PG is often misdiagnosed as an infected wound, but treatment is completely different. We report a case of PG as a complication to arthroscopic partial meniscectomy that resulted in arthrodesis of the knee.

Demographic and socioeconomic risk factors of adult violent victimization from an accident and emergency department and forensic medicine perspective: a register-based case-control study.

Objectives: To describe demographic and socioeconomic risk factors of adult violent victimization leading to contact with an emergency department and/or an institute of forensic medicine based on a case-control study design.

Design: A register-based case-control study comparing demographic and socioeconomic characteristics of 10,799 adult victims of violence (cases) and 53,986 randomly selected population-based controls matched for age, gender, and date.

Data Sources: Cases were included from a Danish emergency department and a Danish institute of forensic medicine.

[Development in violence in Odense City from 1991-2002].

The study included 14,316 consecutive victims of violence registered by Odense University Hospital and/or the Institute of Forensic Medicine, University of Southern Denmark from 1991-2002. The incidence rate was 9.9 and 3.

Trends in deliberate interpersonal violence in the Odense Municipality, Denmark 1991-2002. The Odense study on deliberate interpersonal violence.

A 12-year study was carried out to investigate the development of interpersonal violence based on A and E department and/or forensic data from a Danish urban population. Included in the study were all victims of violence from the Odense municipality treated at the Odense University Hospital or subjected to medicolegal autopsy at the Institute of Forensic Medicine, University of Southern Denmark 1991-2002. Overall 14,316 victims of violence were included in the study.

[Knee arthrodesis with external ring fixator after infected knee arthroplasty].

Introduction: Infection following knee arthroplasty is a severe complication which may lead to arthrodesis or even amputation. We wanted to examine the results after arthrodesis of the knee using the Ilizarov ring fixator in eight patients.

Materials And Methods: Eight patients (seven females, one male) who underwent knee arthrodesis with the Ilizarov external fixator were studied retrospectively.

Correction of congenital brachymetatarsia by gradual callus distraction.

Two children with congenital brachymetatarsia of the fourth metatarsal bone were treated by osteotomy of the metatarsal bone and bone lengthening by the Ilizarov technique. Both children were cosmetically improved.

[Economic coverage and average costs related to injuries treated in a hospital].

Introduction: The purpose of this study was to estimate the average costs of injuries and the proportion of total (treatment + social) costs covered when including injuries treated at the hospital.

Material And Methods: The empirical data consisted of emergency department visits (n = 29,516) from the catchment area of Odense University Hospital in 1992 for all age groups and a representative population sample (n = 1074 injuries) for the age group 15-67 years old. The costs were assessed following the "cost of illness" principles.