Implementation of an algorithm for predicting exacerbations in telemonitoring: A multimethod study of patients' and clinicians' experiences.

Background: Prediction algorithms may improve the ability of telehealth solutions to assess the risk of future exacerbations in patients with chronic obstructive pulmonary disease. Learning from patients' and clinicians' evaluations and experiences about the use of such algorithms is essential to evaluate its potential and examine factors that could potentially influence the implementation and sustained use.

Objective: To investigate the patients' and clinicians' perceptions and satisfaction with an algorithm for predicting exacerbations in patients with chronic obstructive pulmonary disease.

Prediction of Poor Glycemic Control in Children with Type 1 Diabetes.

This study developed and validated a machine learning model for predicting glycemic control in children with type 1 diabetes at the time of diagnosis, revealing age at diagnosis as the most informative predictor.

A telemonitoring intervention design for patients with poorly controlled type 2 diabetes: protocol for a feasibility study.

Background: Maintaining optimal glycemic control in type 2 diabetes (T2D) is difficult. Telemedicine has the potential to support people with poorly regulated T2D in the achievement of glycemic control, especially if the telemedicine solution includes a telemonitoring component. However, the ideal telemonitoring design for people with T2D remains unclear.

The Effectiveness of Digital Health Lifestyle Interventions on People With Prediabetes: Protocol for a Systematic Review, Meta-Analysis, and Meta-Regression.

Background: There has been an increasing interest in the use of digital health lifestyle interventions for people with prediabetes, as these interventions may offer a scalable approach to preventing type 2 diabetes. Previous systematic reviews on digital health lifestyle interventions for people with prediabetes had limitations, such as a narrow focus on certain types of interventions, a lack of statistical pooling, and no broader subgroup analysis of intervention characteristics. The identified limitations observed in previous systematic reviews substantiate the necessity of conducting a comprehensive review to address these gaps within the field.

Evaluation of a phosphate kinetics model in hemodialysis therapy-Assessment of the temporal robustness of model predictions.

In-depth understanding of intra- and postdialytic phosphate kinetics is important to adjust treatment regimens in hemodialysis. We aimed to modify and validate a three-compartment phosphate kinetic model to individual patient data and assess the temporal robustness. Intradialytic phosphate samples were collected from the plasma and dialysate of 12 patients during two treatments (HD1 and HD2).

Implementation of a coagulation component into a phosphate kinetics model in haemodialysis therapy: A tool for detection of clotting problems?

A coagulation component should be considered in phosphate kinetics modelling because intradialytic coagulation of the extracorporeal circuit and dialyser might reduce phosphate removal in haemodialysis. Thus, the objective of this study was to add and evaluate coagulation as an individual linear clearance reduction component to a promising three-compartment model assuming progressive intradialytic clotting. The model was modified and validated on intradialytic plasma and dialysate phosphate samples from 12 haemodialysis patients collected during two treatments (HD1 and HD2) at a Danish hospital ward.

Using machine learning to design a short test from a full-length test of functional health literacy in adults-The development of a short form of the Danish TOFHLA.

Introduction: Patients are compelled to become more involved in shared decision making with healthcare professionals in the self-management of chronic disease and general adherence to treatment. Therefore, it is valuable to be able to identify patients with low functional health literacy so they can be given special instructions about the management of chronic disease and medications. However, time spent by both patients and clinicians is a concern when introducing a screening instrument in the clinical setting, which raises the need for short instruments for assessing health literacy that can be used by patients without the involvement of healthcare personnel.

An Interactive Communication Model for Self-Care-Regardless of Health Literacy: Protocol for a Quasi-Experimental Study.

Background: Clear dialogue-based (interactive) communication that ensures comprehension and recall becomes more important in patient-provider interactions, especially in relation to patients with chronic diseases, where self-management education and counseling are cornerstones in managing these diseases. If patients with chronic disease experience challenges in obtaining, understanding, and applying health-related information (necessary to make informed health decisions and sufficiently manage their health), clear communication and ensuring comprehension become even more critical in the patient-provider interactions. Furthermore, patient-provider communication has been proposed as a potential pathway through which health literacy might influence health outcomes, especially in individuals with chronic diseases.

Patient-Reported Outcomes for Function and Pain in Total Knee Arthroplasty Patients.

Background: Some patients undergoing total knee arthroplasty successfully manage their condition postoperatively, whereas others encounter challenges in regaining function and controlling pain during recovery at home.

Objective: The aim of this study was to use traditional statistics and machine learning to develop prediction models that identify patients likely to have increased care needs related to managing function and pain following total knee arthroplasty.

Methods: This study included 201 patients.

Effectiveness of Telemedicine in Managing Diabetes in Pregnancy: A Systematic Review and Meta-Analysis.

Background: Strict monitoring of blood glucose during pregnancy is essential for ensuring optimal maternal and neonatal outcomes. Telemedicine could be a promising solution for supporting diabetes management; however, an updated meta-analysis is warranted. This study assesses the effects of telemedicine solutions for managing gestational and pregestational diabetes.

The potential of dividing the oxford knee score into subscales for predicting clinically meaningful improvements in pain and function of patients undergoing total knee arthroplasty.

Background: Subdividing the Oxford Knee Score (OKS) into a pain component scale (OKS-PCS) and a function component scale (OKS-FCS) for predicting clinically meaningful improvements may provide a basis for identifying patients in need of enhanced support from health care professionals to manage pain and functional challenges following total knee arthroplasty.

Aim: To assess the potential of dividing the OKS into subscales for predicting clinically meaningful improvements in pre- and postoperative pain and function by comparing two different versions of extracting pain and function derived from the OKS.

Methods: This retrospective observational cohort study included 201 patients undergoing total knee arthroplasty.

Reablement professionals' perspectives on client characteristics and factors associated with successful home-based reablement: a qualitative study.

Background: To understand what is needed to achieve a successful Danish home-based reablement service from the perspective of reablement professionals.

Methods: Semi-structured interviews and observations were conducted with nine professionals within a municipal visitation unit in the Northern Denmark Region. Thematic analysis was used to analyze the interviews.

Preliminary Qualitative Evaluation of Patient-Related Perspectives Related to the Implementation of a Predictive Algorithm in a Telehealth System for COPD.

The aim of the present study was to evaluate patient-related perspectives from a five-week test of the implementation of a COPD prediction algorithm. The test intended to discover and avoid potential errors prior to testing the COPD prediction algorithm in a two-armed randomized controlled trial (RCT). The COPD prediction algorithm aims to predict exacerbations in COPD based on home measurements.

Predictors of Hospital Admissions Based on Routinely Collected Everyday Observations in a Community Care Setting.

The aim of this study was to identify predictors for hospital admissions in community-dwelling adults based on routinely collected community data. Univariate logistic regression analyses were performed to assess each variable's ability to predict preventable and all cause hospital admissions.

Models Used in Clinical Decision Support Systems Supporting Healthcare Professionals Treating Chronic Wounds: Systematic Literature Review.

Background: Chronic wounds such as diabetic foot ulcers, venous leg ulcers, and pressure ulcers are a massive burden to health care facilities. Many randomized controlled trials on different wound care elements have been conducted and published in the Cochrane Library, all of which have only a low evidential basis. Thus, health care professionals are forced to rely on their own experience when making decisions regarding wound care.

Characteristics of Subjects With Undiagnosed COPD Based on Post-Bronchodilator Spirometry Data.

Background: COPD is largely underdiagnosed. Patients with undiagnosed COPD need to be diagnosed to ensure early treatment institution. It is therefore relevant to obtain a more profound understanding of the characteristics of patients with undiagnosed COPD to improve COPD case finding.

A Decision Support Tool for Healthcare Professionals in the Management of Hyperphosphatemia in Hemodialysis.

Hyperphosphatemia is known as one of the more challenging conditions in end-stage renal disease patients. This study set out to present and evaluate a healthcare-oriented decision support tool in the management of hyperphosphatemia within hemodialysis therapy. A prototype module was designed to fit into the interface of a modern dialysis machine (Fresenius 5008).

Phosphate Kinetic Models in Hemodialysis: A Systematic Review.

Background: Understanding phosphate kinetics in dialysis patients is important for the prevention of hyperphosphatemia and related complications. One approach to gain new insights into phosphate behavior is physiologic modeling. Various models that describe and quantify intra- and/or interdialytic phosphate kinetics have been proposed, but there is a dearth of comprehensive comparisons of the available models.

Subgroup analysis of telehealthcare for patients with chronic obstructive pulmonary disease: the cluster-randomized Danish Telecare North Trial.

Purpose: Results from the Danish cluster-randomized trial of telehealthcare to 1,225 patients with chronic obstructive pulmonary disease (COPD), the Danish Telecare North Trial, concluded that the telehealthcare solution was unlikely to be cost-effective, by applying international willingness-to-pay threshold values. The purpose of this article was to assess potential sources of variation across subgroups, which could explain overall cost-effectiveness results or be utilized in future economic studies in telehealthcare research.

Methods: First, the cost-structures and cost-effectiveness across COPD severities were analyzed.

Causes of misdiagnosis of chronic obstructive pulmonary disease: A systematic scoping review.

Background: Chronic obstructive pulmonary disease (COPD) has serious implications at both the individual and the societal level. It is crucial that COPD is diagnosed correctly to ensure provision of the right treatment. However, the current diagnostic procedures may lead to misdiagnosis.

Telehealthcare for patients suffering from chronic obstructive pulmonary disease: effects on health-related quality of life: results from the Danish 'TeleCare North' cluster-randomised trial.

Objective: To assess the effect of telehealthcare compared with usual practice in patients with chronic obstructive pulmonary disease (COPD).

Design: A cluster-randomised trial with 26 municipal districts that were randomly assigned either to an intervention group whose members received telehealthcare in addition to usual practice or to a control group whose members received usual practice only (13 districts in each arm).

Setting: Twenty-six municipal districts in the North Denmark Region of Denmark.

Probing community nurses' professional basis: a situational case study in diabetic foot ulcer treatment.

Complicated and long-lasting wound care of diabetic foot ulcers are moving from specialists in wound care at hospitals towards community nurses without specialist diabetic foot ulcer wound care knowledge. The aim of the study is to elucidate community nurses' professional basis for treating diabetic foot ulcers. A situational case study design was adopted in an archetypical Danish community nursing setting.

An Iterative, Mixed Usability Approach Applied to the Telekit System from the Danish TeleCare North Trial.

. The aim of the present study is to evaluate the usability of the telehealth system, coined Telekit, by using an iterative, mixed usability approach. .

Participatory Heuristic Evaluation of the Second Iteration of the eWALL Interface Application.

The number of people having a chronic disease is increasing. Telehealth may provide an alternative to traditional medicine as telehealth solutions have shown to have a positive influence on quality of live and to decrease the number of hospital visits. A new telehealth solution is the eWALL system.

Specific technological communication skills and functional health literacy have no influence on self-reported benefits from enrollment in the TeleCare North trial.

Purpose: The Danish TeleCare North trial has developed a telehealth system, Telekit, which is used for self-management by patients diagnosed with chronic obstructive pulmonary disease (COPD). Self-management is the engagement in one's own illness and health by monitoring and managing one's symptoms and signs of illness. The study examines the association between COPD patients' use of Telekit and their functional health literacy and the association between their use of Telekit and their specific technological communication skills.