Antioxidant supplementation for sickle cell disease.

Background: Sickle cell disease (SCD) refers to a group of genetic disorders characterized by the presence of an abnormal haemoglobin molecule called haemoglobin S (HbS). When subjected to oxidative stress from low oxygen concentrations, HbS molecules form rigid polymers, giving the red cell the typical sickle shape. Antioxidants have been shown to reduce oxidative stress and improve outcomes in other diseases associated with oxidative stress.

A 5-year review of pattern of placenta previa in Ilorin, Nigeria.

Background: Placenta previa, a major cause of obstetric hemorrhage, is potentially life-threatening to the mother and frequently results in high perinatal morbidity and mortality.

Methodology: This is a retrospective study of all cases of placenta previa managed at the University of Ilorin Teaching Hospital over a 5-year from January 2011 to December 2015. A pro forma template was used to harvest information from case notes of patients involved in the study.

Mullerian Agenesis with Primary Amenorrhea: A Case Report of a Normal Phenotypic Female.

Meyer-Rokitansky-Kuster-Hauser syndrome is a rare congenital abnormality occurring sporadically in females. It is the most common cause of primary amenorrhea. Affected persons usually appear normal on physical examination.

Attitudes to female genital mutilation/cutting among male adolescents in Ilorin, Nigeria.

Background: The central role of males in female reproductive health issues in patriarchal societies makes them an important group in the eradication of female genital mutilation/cutting (FGM/C).

Objective: To determine knowledge about and attitudes to FGM/C among male adolescents, and their preparedness to protect their future daughters from it.

Methods: A cross-sectional survey among male adolescent students in Ilorin, Nigeria.

Missed Diagnosed Bicornuate Unicollis Uterus Presenting As Acute Abdomen.

Uterus bicornuate unicollis is one of the various congenital abnormalities of the female genital tract caused by partial fusion of the mullerian ducts on both sides. A case of acute abdomen resulting from missed diagnosed bicornuate unicollis uterus in a 42-year infertile women was presented. The ultrasonographic diagnosis of twisted complex left adnexial cyst was made prior to exploratory laparotomy.

Prevalence of anaemia at booking in a semi-urban community in north-central Nigeria.

Aims And Objectives: This study was carried out to determine the prevalence of anaemia at booking clinic, describe the antenatal booking pattern, and categorize the degree of anaemia with certain demographic features.

Subjects And Methods: This is a descriptive cross-sectional study carried out over a six month period between 1st April and 30th September 2008. A questionnaire was used to obtain demographic information and venous blood samples were collected from 1,086 consecutive patients who consented to participate in the study.

Significance of IgG-Avidity in Antenatal Rubella Diagnosis.

Objective: A descriptive study was carried out to determine the significance of IgG-affinity in the serological diagnosis of rubella infections in pregnancy.

Materials And Methods: A total of 92 pregnant women who had never received antirubella vaccines were recruited by simple random selection and did not exceed 24 weeks of gestation were recruited from the antenatal clinics of the University of Ilorin Teaching Hospital. Rubella virus-specific IgG, IgG-affinity and IgM were tested, using the Indirect ELISA methods.

Ectopic pregnancy in Ilorin, Nigeria: a four year review.

Aims And Objectives: This is to study the incidence, predisposing factors, clinical presentation and management of ectopic pregnancy that presented over a four year period.

Patients, Materials And Methods: This is a retrospective study of 98 ectopic pregnancies managed at the gynaecological unit of University of Ilorin Teaching Hospital, Ilorin from 1st January 2004 to 31st December 2007. Information was obtained from the case notes, theatre and labour ward registers.

Repeat caesarean delivery as a risk factor for abnormal blood loss, blood transfusion and perinatal mortality.

We reviewed 450 cases of caesarean delivery (January-December 2009) at the University of Ilorin Teaching Hospital in Nigeria. We analysed the association between caesarean delivery status (primary or previous) and the following outcomes: abnormal blood-loss, blood transfusion and perinatal mortality. Although significant differences were observed between primary and previous caesarean delivery groups in regards to maternal age, urgency of the caesarean delivery, booking status, and cadre of birth attendant staff, no association was noted between caesarean delivery status and any of the three outcomes.

Duration of labor with spontaneous onset at the University of Ilorin Teaching Hospital, Ilorin, Nigeria.

Background/objective: Duration of labor varies from one pregnancy to another and a period of less than 12 hours is regarded as normal. Modern obstetric practice involves active management of labor with the aim of preventing prolonged labor and its sequelae. The main objective of this study was to determine and compare the average duration of labor of spontaneous onset between nulliparas (Po) and multiparas (P ≥ 1) and to determine factors affecting duration of labor.

Hepatitis B virus infection amongst pregnant women in North-eastern Nigeria- a call for action.

Background: It is well known that Hepatitis B virus infection is endemic in Nigeria. Even though studies have been carried out on Hepatitis B virus infection in different parts of Nigeria, and in different sub-groups of individuals, information regarding the prevalence of Hepatitis B virus infection in pregnant women is scanty especially from the North-eastern region of Nigeria. We therefore determined the seroprevalence of Hepatitis B surface antigen (HBsAg) amongst pregnant women in North Eastern Nigeria.

Vesicovaginal fistula: a review of nigerian experience.

Background: Vesicovaginal fistula is a preventable calamity, which has been an age-long menace in developing countries.

Objective: To review the causes, complications, and outcome of Vesicovaginal fistula in Nigeria.

Methods: Studies on Vesicovaginal fistula were searched on the internet.

Premenstrual dysphoric disorder among medical students of a Nigerian university.

Background/objective: This study aimed at estimating the prevalence and associated factors of premenstrual dysphoric disorder (PMDD) among medical students in a University in the North-Central State of Nigeria. PMDD is the severest form of premenstrual symptoms and is associated with impairment of social and role functioning.

Methods: A cross-sectional study of female medical students of the University of Ilorin College of Health Sciences (n=208), which involves completing a questionnaire to elicit socio-demographic and gynecological information as well as the GHQ-12 questionnaires.

Estimating the impact of birth control on fertility rate in sub-Saharan Africa.

Using a cross-country data drawn from 40 countries and a multiple regression analysis, this paper examines the impact of birth control devices on the rate of fertility in sub-Saharan Africa. Our a-priori expectations are that the more women used birth control devices, the less will be the fertility rate in sub-Saharan Africa. The result obtained from the study indicates that except for withdrawal method that fall contrary to our expectation other variables (methods) like the use of pills, injection, intra uterine device (IUD), condom/diaphragm and cervical cap, female sterilization and periodic abstinence/rhythm fulfilled our a-priori expectations.

Thyroid diseases in pregnancy: a review.

Objective: To provide an overview of the pathophysiology of thyroid diseases in pregnancy and the various treatment methods currently available in its management.

Data Source: Review of literature was affected through index medicus search of major published journals and books.

Data Selection: Published data on thyroid diseases on women in the reproductive age group over the last four decades were utilised.

Anovulatory infertility: a report of four cases and literature review.

Four cases of anovulatory/dysovulatory infertility encountered in Ilorin, Nigeria are presented and the literature extensively reviewed on the up-to-date management of this aspect of infertility. All the patients had bilateral tubal patency on hysterosalpingography (HSG) and their husbands had normal seminal fluid analysis. The first case, 30 years of age, had hyperprolactinaemia with galactorrhoea, treated with bromocriptine given 2.

Intrauterine contraceptive device (IUCD): socio-demographic characteristics of acceptors, acceptability and effectiveness in a teaching hospital in Nigeria.

This paper reports the socio-demographic characteristics of acceptors and their experience with intrauterine contraceptive device (IUCD) at the University of Ilorin Teaching Hospital Family Planning Clinic between January 1st, 1992 and December 31st, 1992. A total of 1,483 new contraceptive acceptors were seen at the Family Planning Clinic during the period of study of which 822 (55.4%) were first segment IUCD acceptors.

Obesity--an overview.

Obesity or being overweight, often resulting from overfeeding, has become a problem of public health magnitude not only in the developed countries but also in the developing countries. The literature has been extensively reviewed to give an overview of the health problems associated with this disorder. Some of these health hazards include hypertension, stroke, coronary (ischaemic) heart disease, diabetes mellitus, premature death, increased risk of cancer and at surgery.