Publications by authors named "Olallo Sanchez-Molero"
Background: Sudden cardiac death is a natural and unexpected death that occurs within 1 h of the first symptom. Most sudden cardiac deaths occur during exercise, mostly as a result of myocardial infarction. After autopsy, some cases, especially in the young, are diagnosed as cardiomyopathies or remain without a conclusive cause of death.
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- Sudden cardiac arrest, a major cause of death globally, often occurs in patients with a history of myocardial infarction, with certain genetic factors potentially increasing this risk.* * A study of 56 post-mortem samples found myocardial infarction was the cause of death, and genetic sequencing revealed six rare missense variants in cardiac ion channels among five patients.* * The findings included one deleterious variant (RyR2_p.M4019T) and two previously noted variants, yet the broader clinical implications of these genetic changes remain unclear, necessitating further research in larger patient groups.*
Article Synopsis
- * Out of 29 cases analyzed, 35 genetic variants were found in 12 cases (41.37%), with notable findings in genes related to cardiac ion channels and structural proteins.
- * The findings advocate for incorporating molecular autopsy into forensic protocols, as many cases (around 40%) could reveal genetic variants explaining sudden death, emphasizing the importance of screening for at-risk relatives.
An aging population, emerging technology, heightening patient expectations, rising health care costs, shorter patient stays, and growing pressure to improve quality have made the management of nursing resources even more critical today. While approaching a model for staffing levels, the authors considered factors such as patient acuity, work redesign, and minimum quality standards. The methodology for analysis included estimating the time needed to complete nursing tasks and calculating the average number of tasks per patient.
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