Publications by authors named "Olalla Martinez-Macias"
Article Synopsis
- SERINC5 plays a crucial role in limiting certain viruses' infectivity, but its regulation during viral infection, especially with SARS-CoV-2, is not well understood.
- Recent findings show that SERINC5 levels drop in COVID-19 patients, and this decrease might be linked to small viral RNAs (svRNAs) produced by SARS-CoV-2, which can bind to SERINC5 mRNA and lower its expression.
- Anti-svRNA treatments could potentially restore SERINC5 levels and reduce viral protein levels, suggesting a new therapeutic approach for enhancing the innate immune response during COVID-19.
Objectives: To describe clinical characteristics of fracture patients, including a closer look to hip fracture patients, and determine how epidemiological variables may have influenced on a higher vulnerability to SARS-CoV-2 infection, as the basis for the considerations needed to reintroduce elective surgery during the pandemic.
Design: Longitudinal prospective cohort study.
Setting: Level I Trauma Center in the East of Spain.
[Situation of pertussis in Valencian Community: an epidemic revival?].
Enferm Infecc Microbiol Clin
November 2013
Introduction: Pertussis is a highly contagious vaccine-preventable disease. An increasing incidence has been reported in several countries around the world in the last few years. The aim of this study is to analyze the situation of pertussis in the Valencian Community (Spain), with the purpose of verifying the increased incidence of the illness.
View Article and Find Full Text PDFBackground: Listeria monocytogenes is an uncommon cause of disease, although in certain age groups (infants, elderly, pregnant women and immunocompromised) may be an important cause of meningoencephalitis, and bacteremia. The aim of this study was to detect the incidence of invasive listeriosis cases found in Valencia during a period of 3 years.
Methods: A retrospective study of invasive listeriosis detected in the period 2008-2010 was carried out.