Publications by authors named "Olaitan E Oladipupo"
Article Synopsis
- Researchers investigated protic ruthenium complexes with dihydroxybipyridine (dhbp) ligands and spectator ligands (like bpy and phen) to evaluate their effectiveness against cancer cells and their luminescent properties.
- The study focuses on 16 complexes derived from two protonation states (acidic and deprotonated), including new complexes that were synthesized and characterized through spectroscopy and X-ray crystallography.
- Key findings show that certain complexes can be activated by light to exhibit photocytotoxicity, with specific complex characteristics such as longer luminescent lifetimes correlating with improved effectiveness against cancer cells.
This review focuses on light-activated ruthenium anticancer compounds and the factors that influence which pathway is favored. Photodynamic therapy (PDT) is favored by π expansion and the presence of low-lying triplet excited states (e.g.
View Article and Find Full Text PDFWe report new ruthenium complexes bearing the lipophilic bathophenanthroline (BPhen) ligand and dihydroxybipyridine (dhbp) ligands which differ in the placement of the OH groups ([(BPhen) Ru(n,n'-dhbp)]Cl with n = 6 and 4 in 1 and 2 , respectively). Full characterization data are reported for 1 and 2 and single crystal X-ray diffraction for 1 . Both 1 and 2 are diprotic acids.
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