Publications by authors named "Olafur Einarsson"

Objectives: Glucocorticoid steroids are frequently prescribed, and side effects are well-known, such as glucocorticoid-induced osteoporosis. Our aim was to estimate the nationwide trend in the prevalence of glucocorticoid steroid prescriptions over 17 years and to elucidate the proportion of patients on long-term glucocorticoid steroid therapy who receive active bone protective therapy. As well as to examine which medical specialties prescribe glucocorticoid steroids the most.

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Recent studies have suggested that protected areas often fail to conserve target species. However, the efficacy of terrestrial protected areas is difficult to measure, especially for highly vagile species like migratory birds that may move between protected and unprotected areas throughout their lives. Here, we use a 30-y dataset of detailed demographic data from a migratory waterbird, the Whooper swan (), to assess the value of nature reserves (NRs).

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Background: Primary non-adherence refers to the patient not redeeming a prescribed medication at some point during drug therapy. Research has mainly focused on secondary non-adherence. Prior to this study, the overall rate of primary non-adherence in general practice in Iceland was not known.

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Unlabelled: Breast reduction is an established and effective operation in reducing symptoms of macromastia (Hyperplasia mammae). This is one of the most common operation done by plastic surgeons today.

Objective: The purpose of this retrospective descriptive analysis was to determine the results of bilateral reduction mammaplasty in the period 1984-1993, at the department of Plastic Surgery, National University Hospital, Reykjavík, Iceland.

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We previously mapped susceptibility to stroke to chromosome 5q12. Here we finely mapped this locus and tested it for association with stroke. We found the strongest association in the gene encoding phosphodiesterase 4D (PDE4D), especially for carotid and cardiogenic stroke, the forms of stroke related to atherosclerosis.

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Article Synopsis
  • Stroke is a complex disease with various subtypes and multiple secondary risk factors like hypertension and diabetes, which have their own genetic and environmental influences.
  • Researchers conducted a genomewide search for genes that might increase susceptibility to common stroke forms by analyzing data from stroke patients in Iceland and a genealogy database, identifying 476 patients within 179 extended families.
  • A significant discovery was made on chromosome 5q12, with a high LOD score indicating strong evidence for a genetic link to stroke; this region, named "STRK1," is novel and not previously associated with known stroke susceptibility loci.
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