Background: In our continued search for bioactive compounds from plants, conscious effort is being made to rapidly analyze ethnobotanical plants used for treating various ailments by traditional healers before this information is irrevocably lost as societies advance and rural communities become urbanized.
Results: A compound isolated from the aqueous extract of Pavetta crassipes leaves showed activity against some pathogenic microorganisms which included Streptococcus pyogenes, Corynebacterium ulcerans, Klebsiella pneumoniae, Neisseria gonorrhoeae, Pseudomonas aeruginosa, and Escherichia coli at a concentration < 50 mg/mL. The compound had minimum inhibitory concentration ranging from 6.