Publications by authors named "Ola Shahin"
Background: The aim of the study was to assess the health-related quality of life (HRQOL) and cognitive function in patients with Crigler-Najjar syndrome (CNS) type I and its impact on their lives.
Methods: Twenty-one patients diagnosed with CNS type I aged 1 month to 18 years in the Paediatric Hepatology Unit of Cairo University Children's Hospital were enrolled in this cross-sectional observational study. The patients' health-related quality of life (HRQOL) was assessed using the World Health Organization Quality Of Life BREF questionnaire (WHOQOL-BREF) and the Short Form 36 Health Survey Questionnaire (SF-36).
Article Synopsis
- - The study aimed to examine how Electroconvulsive Therapy (ECT) affects plasma BDNF levels in patients with resistant schizophrenia, comparing those who received ECT and those who continued with standard antipsychotic treatment.
- - Results showed that patients receiving ECT had a significant increase in BDNF levels after treatment, while those on antipsychotics only had a non-significant increase; both groups experienced improvements in psychotic symptoms.
- - The findings suggest that ECT can enhance plasma BDNF levels and promote clinical improvement in resistant schizophrenia, although BDNF levels did not correlate with the severity of symptoms.
Introduction: The variable number of tandem repeats (VNTR) of the dopamine receptor D4 (DRD4) gene among humans may elucidate individual differences in susceptibility to neuropsychiatric diseases. Dopamine dysfunction may be involved with Attention Deficit Hyperactivity Disorder (ADHD) symptoms. In this study, we report the association between the phenotype of ADHD, a condition characterized by inattentiveness, hyperactivity, and impulsiveness, and a 48-base pair VNTR in exon 3 of the DRD4 polymorphism.
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