Publications by authors named "Ola A Shaqroon"
Article Synopsis
- - The MLL1 gene, found on chromosome 11q23, is important for methylating histones and is linked to different types of leukemia, but there's limited research on how Single Nucleotide Polymorphisms (SNPs) affect its protein structure and function.
- - Utilizing bioinformatics tools, researchers analyzed over 2,000 nsSNPs in MLL1, finding 62 that could significantly affect protein function and stability, with four identified as likely contributing to cancer.
- - The study highlights how certain SNPs, like D2724G, may alter protein pathways related to cancer, emphasizing the need for more personalized treatment approaches and better understanding of leukemia development.
