[Heart failure and imbalance of chemical elements in myocardium of patients with ishemic heart disease].

Tissue content of chemical elements indirectly characterizes some metabolic processes. We have analyzed content of chemical elements in left and right ventricular myocardium of patients with ischemic heart disease with progressing heart failure and have shown that during development and progression of heart failure metabolic processes have unidirectional character in myocardium of both ventricles. Derangement of left ventricular contractile capacity is associated with lowering of content of microelements involved in antioxidant processes and energy metabolism in tissues (Cu, Mn, Cr) and elevated concentration of elements characterizing progressive of myocardial stiffness (Ca, Fe).

[Zoobenthos communities and their seasonal dynamics in nonfreezing springs of Baikal region].

The faunal composition, structure of the zoobenthos communities, and seasonal changes in two springs in the south of Irkutsk area are investigated. Both springs have the water temperature 4-5 degrees C all year round. The fauna consists of widely distributed hydrobionts, crenobionts, stygobionts, and near-water organisms.

[Comparative characteristics of quality of life and physical status of patients with ischemic heart disease and aortic valve disease].

For comparison of physical status and quality of life of patients we analyzed 2 clinical groups: patients with ischemic heart disease (IHD) and aortic valve disease. Using original methodology of bringing results of questionnaire " Nottingham Health Profile " to functional classification we had a possibility to compare quality of life of patients with functional classes of physical working capacity and NYHA classification. Subjective component inserted into NYHA classification and quality of life questionnaire leads to substantial discrepancy with objective data on physical working capacity.

Anatomical variants of transposition of the main vessels and their relationship with the content of chemical elements in heart ventricles.

Cardiometrical characteristics of anatomical variants of the main vessels transposition are determined by different functional load of heart compartments and are associated with metabolic processes of different intensity, which is confirmed by the content of chemical elements in the right- and left-ventricular myocardium. It was shown that the content of chemicals was virtually the same in both cardiac ventricles in case of main vessels transposition and isolated atrial septal defect. Positive correlations between the degree of left-ventricular hypertrophy and content of S, K, Fe, and Sr in it and a negative correlation between this hypertrophy and Cu content were revealed.

[Distribution of chemical elements in various parts of the heart of patients with acute heart failure].

By the method of autopsy in patients with ischemic heart disease (IHD) who died of acute heart failure we took samples of myocardium from 6 parts of the heart: left and right atrium, left and right ventricle, region of myocardial infarction, and scar of the left ventricle. Simultaneously we conducted histological study of these parts of myocardium. For the control we investigated content of chemical elements in myocardium of healthy victims of traffic accidents.

[Stages of compensation of circulation in acquired aortic valve disease according to data of physical working capacity].

We examined 194 men (mean age 40 +/- 1.4 years) with acquired aortic valve disease. Basing on the data of estimation of physical working capacity and reserve of cardiorespiratory system we assessed staging of development of compensatory mechanisms of circulation in patients with acquired aortic stenosis and aortic insufficiency.

Role of chemical elements in formation of an aortic aneurysm.

The method of X-ray fluorescence employing synchronous radiation was used to study the content of chemical elements (CE) in the aortic wall in patients suffering from CAD (Group I), patients diagnosed with an ascending aortic aneurysm (Group II), and those presenting with aortic dissection (Group III). The obtained findings revealed a pronounced CE disbalance in the aortic wall in Group II and III patients as compared with Group I patients, suggesting an important role of trace and macroelements in metabolic processes related to formation of artic aneurysms. Based on the degree of the ascending aorta dilatation, we determined the coefficient of the ratio of the ascending aorta maximal diameter to the fibrous ring aortic valve diameter, equalling 1.

[Content of microelements in left ventricular myocardium of patients with ischemic heart disease. Data of roentgenofluorescent analysis with the use of synchrotron irradiation].

Contents of 11 microelements (Se, Rb, K, Sr, Ca, Cr, Mn, Fe, Cu, Ni, Zn) in various parts (zone of infarction, of scar, periinfaction zone) of left ventricular myocardium of patients with ischemic heart disease was studied with method of rentgenofluorescent analysis with the use of synchrotron irradiation (overall 2112 analyses). Left ventricular myocardium of victims of accidents without cardiovascular pathology was studied as control. Compared with control dysbalance of various degree was noted in left ventricular myocardium of patients with ischemic heart disease.

[The study of cerebral oxygenation and central hemodynamics in patients with ischemic heart disease at rest and during physical effort.].

Cerebral oxygenation (rSO(2)) in the region of sagittal sinus and main hemodynamic parameters were measured in 112 patients with ischemic heart disease and class II-III angina. Four groups of patients were distinguished according to degree of rSO(2) lowering. Hemodynamics and oxygen transport function of the blood were proportionally related to degree of rSO(2) lowering.

Laser Doppler flowmetry assessment of microcirculation in upper extremities before and in long-term period after harvesting of radial artery.

Radial artery (RA) is rather commonly used as a graft for autoarterial myocardial revascularization. Consequences of RA harvesting for the development of ischemic disturbances in distal hand segments are poorly understood. The paper presents assessment of hand microcirculation (HMC) before and in late postoperative period after RA harvesting with modern precise diagnostic method - laser Doppler flowmetry (LDF).

[Myocardial blood flow in different regions of the heart in patients with ischemic heart disease before and after revascularization].

Laser doppler flowmetry was used for the intraoperative study of myocardial blood flow before and after revascularization in 116 patients with 2-3 vessel coronary artery disease and class II-IV angina. In patients without myocardial infarction, with microfocal myocardial infarction, or operated early after myocardial infarction revascularization caused no significant increase of myocardial blood flow. In patients with macrofocal infarction surgery was associated with significant increase of myocardial blood flow.

[The sequelae and late results of surgical treatment in wounds of the heart and pericardium].

An examination of 109 patients after surgical treatment of wounds of the heart and pericardium were performed at late terms after treatment. It was found that good results had 53.2% of the patients, 12.

[Clinico-physiological assessment of the mechanisms of compensation and paracompensation in patients with mitral stenosis].

The paper presents the results of an examination of 292 patients with Stages II-V mitral stenosis. Clinical, roentgenological, and electrocardiographic characteristics of the defect were analysed. Physical fitness and gas exchange during exercise were studied in 183 patients with Stages III and IV mitral stenosis.

[Blood oxygen saturation in various regions of the circulatory system in healthy persons].

The gaseous composition of the blood has been determined in cardiac cavities and major vessels in 180 practically healthy individuals aged from 1 to 30 years, during diagnostic catheterization of the heart. Physiological norms of gaseous composition of the blood in cardiac cavities and in the major blood vessels have been determined. Blood saturation with oxygen in the identical cardiac cavities and the major blood vessels are the same in men and women.