Publications by authors named "Okuma S"

Article Synopsis
  • Traumatic optic neuropathy (TON) is a rare but serious condition leading to vision impairment, often resulting from facial trauma, emphasizing the need for effective diagnosis and treatment methods.
  • A study analyzed four patients (average age 75) with midfacial fractures and TON, assessing their visual deficits and outcomes following navigation-assisted endoscopic trans-nasal optic nerve decompression (ETOND) treatment.
  • Results showed that patients with pre-operative vision loss experienced post-operative improvement, with no complications arising from the procedures, highlighting the effectiveness of ETOND in managing TON.
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Correction of coagulation is a crucial aspect of trauma care. While there are reports highlighting the effectiveness of fibrinogen concentrate in severe trauma cases with coagulopathic complications, literature on its use in pediatric cases remains limited. This paper discusses the case of a 5-year-old male presenting with a splenic injury and associated coagulopathy.

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Oral and maxillofacial trauma is influenced by various factors, including regional characteristics and social background. Due to the coronavirus disease 2019 (COVID-19) pandemic, a state of emergency was declared in Japan in March 2020. In this study, we aimed to examine the dynamics of patients with oral and maxillofacial trauma over a 12-years period using interrupted time-series (ITS) analysis.

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Immune checkpoint inhibitors are known to produce immune-related adverse events(irAE)that require medical management. Herein, we report a case of a patient treated with pembrolizumab who experienced a Grade 3 interrupted skin disorder. The patient is a 67-year-old female diagnosed with right maxillary gingival squamous cell carcinoma(cT4aN0M0, Stage ⅣA)and underwent partial right maxillectomy, right extended supra-omohyoid neck dissection, and maxillary reconstruction using a forearm flap.

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Article Synopsis
  • The superconductor-insulator transition (SIT) in two dimensions represents a key quantum phase transition with a quantum critical point at absolute zero temperature (T=0).
  • In certain weakly disordered or crystalline thin films, an anomalous metallic (AM) state shows up between superconducting and insulating states, complicating the traditional QPT understanding of SIT.
  • Measurements of the Nernst effect reveal a ghost-temperature line marking a thermal-to-quantum crossover, helping to locate the QCP within the AM state, thereby suggesting that the AM state is a critical extension of the SIT.
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Radical tumor resection for oral cancer can cause morphological and esthetic disorders and oral and maxillofacial dysfunction and maintaining a social life could become challenging, especially in the adolescents and young adults(AYA)generation. Conversely, chemoradiotherapy for young patients may cause adverse reactions such as impaired fertility and late side effects of radiation. Therefore, treatment should be performed cautiously.

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Article Synopsis
  • Advanced lower gingival carcinoma treatment often requires postoperative chemoradiotherapy, making simultaneous hard-tissue reconstruction less favorable; instead, precarious mandibular reconstruction methods are employed.
  • The study discusses two cases of mandibular reconstruction using a novel custom-made system (Cosmofix®) alongside skin flaps in patients with advanced lower gingival carcinoma.
  • Both patients showed minimal complications post-surgery, with good results in facial morphology and functionality, highlighting the effectiveness of the Cosmofix® system in reconstructive surgery.
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Dysphagia is a major postoperative complication in patients with locally advanced oral cancer. In this case report, we describe the effect of the hyoid bone suspension technique on the preservation of swallowing function after total glossectomy and pectoralis major musculocutaneous flap reconstruction for locally advanced tongue cancer. Case: A 72-year-old Japanese male was diagnosed with advanced squamous cell carcinoma on the left side of his tongue(cT4aN2cM0, cStage ⅣA).

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Dynamical ordering from a disordered plastic flow to an anisotropically ordered smectic flow induced by a dc force has been studied in various many-particle systems, including vortices in type-II superconductors. However, it remains unclear whether the dynamical ordering is a true phase transition because of lack of suitable experimental methods. Here, we study the response of vortex flow to the transverse force using a cross-shaped amorphous Mo[Formula: see text]Ge[Formula: see text] film.

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Non-bacterial thrombotic endocarditis (NBTE) is a condition that results in the development of vegetation on cardiac valves that are devoid of inflammation and bacteria. We herein report a 60-year-old man who transferred to our hospital because of a systemic embolism and heart failure. A mass in the right atrium and vegetation on the mitral valve were observed.

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Key Clinical Message: A case of dentinogenic ghost cell tumor occurring simultaneously with a clinically diagnosed odontoma. The occurrence of epithelial and mesenchymal tumors at the same site is very rare, but should be kept in mind during pathological diagnosis.

Abstract: Dentinogenic ghost cell tumor (DGCT) is a rare and benign odontogenic tumor composed of ghost cells, calcified tissue, and dentin.

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The high perimandibular approach is a feasible surgical technique for treating mandibular condylar fractures with open reduction and internal fixation, followed by fewer complications. Temporary trismus is the only postoperative complication that may occur. This study evaluated postoperative complications following open reduction and rigid internal fixation (OR-IF) of mandibular condylar fractures using the high perimandibular approach.

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Multidisciplinary treatment, combining ablative surgery and reconstruction, radiotherapy, and chemotherapy, is used to treat advanced oral cancers. In this study, we report a case of extensive osteoradionecrosis of the mandible following multidisciplinary treatment for tongue cancer, in which a computer-assisted, patient-specific custom-made cutting guide and reconstruction plate(TruMatch® )were used to improve the patient's facial morphology and oral-maxillofacial functioning. A 70-year-old man received multidisciplinary treatment for squamous cell carcinoma of the left side of the tongue (cT3N2bM0, cStage ⅣA)at a previous hospital.

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Article Synopsis
  • A 74-year-old male patient with advanced lower gingival carcinoma was treated using a computer-assisted custom-made surgical guide and reconstruction plate system called TruMatch® in combination with a pectoralis major myocutaneous flap.
  • The patient’s condition, complicated by paraplegia, necessitated a minimally invasive surgical approach, which included tracheostomy, left modified radical neck dissection, and segmental mandibulectomy.
  • At 18 months post-operation, the patient shows a good prognosis with minimal dysfunction, highlighting the effectiveness of this advanced surgical technique.
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We report a case of cavernous sinus metastasis following postoperative maxillary gingival squamous cell carcinoma. An 83-year-old man was referred to our hospital due to pain in the left maxillary gingiva. Contrast-enhanced computed tomography imaging showed a mass lesion with bone destruction in the left maxillary gingiva.

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In April 2020, a state of emergency was declared because of the pandemic, and the public was instructed to refrain from leaving their homes. Consequently, this stirred up anxiety about visiting medical institutions. Here, we describe a case of tongue carcinoma that developed from an oral precancerous lesion into a malignant transformation owing to the effects of refraining from medical examinations caused by the pandemic.

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Recently, the number of survivors that had oral cancer has increased, but deterioration in the quality of life of patients concerning oral function and cosmetic appearance has become problematic. Prosthodontic dentures usefully treat jaw defects after maxillary resection for cancer, but advances in microsurgery have rendered the possibility to reconstruct maxillary defect and oral cavity using a microvascular flap. Here, we describe 2-stage treatment after 35 years postoperatively.

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The Kibble-Zurek mechanism describes the formation of topological defects in systems crossing a continuous symmetry-breaking phase transition at a finite quench rate. While this mechanism has been extensively studied for equilibrium transitions, its applicability to nonequilibrium transitions has not yet been fully examined. Recent simulation has shown the applicability of the Kibble-Zurek mechanism to dynamical ordering transitions in particlelike assemblies, including superconducting vortices, driven over random disorder.

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Patients with oral cancer have poor nutritional status before treatment. However, there have been no reports of the detailed evaluation of preoperative oral function in patients with oral squamous cell carcinoma (OSCC). Therefore, this study aimed to evaluate the preoperative oral function of patients with OSCC and examine the relationship with nutritional status.

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Oral dysfunction and dysphagia after oral cancer treatment are linked to altered nutritional status. We aimed to identify specific oral functions related to nutritional status. We conducted a cross-sectional study from September 2019 to December 2021, recruited 75 participants (median age: 72.

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Article Synopsis
  • The study examines the consistency between subjective and objective evaluations of postoperative oral dysfunction in oral cancer patients.
  • A total of 75 patients were assessed using the POD-10 questionnaire for subjective evaluation and Matsuda-Kanno classification for objective evaluation, revealing various degrees of agreement between the two methods.
  • Findings indicate that while evaluations for occlusal oral dysfunction were fairly consistent, other types of dysfunction showed potential for misestimation by both patients and medical professionals.
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We study the critical dynamics of vortices associated with dynamic disordering near the depinning transitions driven by dc force (dc current I) and vortex density (magnetic field B). Independent of the driving parameters, I and B, we observe the critical behavior of the depinning transitions, not only on the moving side, but also on the pinned side of the transition, which is the first convincing verification of the theoretical prediction. Relaxation times, [Formula: see text] and [Formula: see text], to reach either the moving or pinned state, plotted against I and B, respectively, exhibit a power-law divergence at the depinning thresholds.

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Article Synopsis
  • A case study details an 81-year-old woman recovering functional use of her lower lip after undergoing incisional cheiloplasty due to edema caused by previous cancer treatments.
  • After a series of surgeries and chemoradiotherapy for maxillary gingival cancer and cervical lymph node recurrence in 2013, the patient experienced labial dysfunction.
  • The cheiloplasty procedure was performed in October 2020, resulting in improved lip closure and satisfaction with labial function seven months post-operation.
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Radical excision, a common oral cancer treatment, produces variable postoperative results depending on the specialized tissues involved and the extent of the cancer. Furthermore, the material selected for reconstruction also influences functional outcomes. Oral dysfunction due to postoperative tissue loss is more common with advanced cancer; therefore, early detection and treatment are important.

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