Objective: Introduction: According to the 2003 WHO report, dental caries affects from 60% to 90% of school-age children and adults that makes it one of the most common diseases worldwide. The aim was to systematize data about the modern conception of plaque formation and role of microorganisms in its development.
Patients And Methods: Materials and methods: Biblosemantic, 50 medical literature sources were systematically reviewed as the material for the research.