Effects of Polyoxidonium on Phagocytic Cell Functions. Experimental and Clinical Estimation of Potential Inclusion of Polyoxidonium in Complex Therapy in Penetrating Eye Injury.

The purpose of present paper is the investigation of polyoxidonium effects on the functions of circulating pool of phagocytic cells and the estimation of its potential inclusion in complex therapy in penetrating eye injuries. On experimental model of eye injuring in rats there has been established that polyoxidonium attenuated some negative glucocorticoid effects on phagocytic cells. Inclusion of polyoxidonium in complex therapy optimized the course of injuring process according to parameters of the least infiltration of damage area with immunocompetent and effector cells, scar structure and other parameters.