Synopsis of recent research by authors named "Oksana Holian"
- Oksana Holian's research primarily focuses on the roles of bioactive lipids, particularly lysophosphatidylcholine (LPC), in lung inflammation and endothelial cell function, with findings indicating that LPC is elevated in conditions such as asthma and acute lung injury, promoting inflammatory responses.
- Her investigations also extend to the regulatory functions of p120 catenin in endothelial cells, showing that loss of this protein can upregulate pro-inflammatory adhesion molecules, highlighting its role beyond cell adhesion to include transcriptional regulation.
- Additionally, Holian has explored the effects of dietary compounds like resveratrol and selenium in cancer contexts, demonstrating their potential in inducing apoptosis and modulating cell proliferation in gastric cancer cells, suggesting their chemopreventive and therapeutic benefits.
