Publications by authors named "Oksana F Tregub"
Article Synopsis
- - The review explores how resistance to low oxygen (hypoxia) may be linked to longer life spans and examines how carbon dioxide affects the aging process in mammals.
- - It highlights the potential synergistic effects of carbon dioxide and hypoxia on aging mechanisms, particularly in the nervous system.
- - The article discusses the future possibilities of using hypercapnic-hypoxic methods as training strategies to promote active longevity.
The review introduces the stages of formation and experimental confirmation of the hypothesis regarding the mutual potentiation of neuroprotective effects of hypoxia and hypercapnia during their combined influence (hypercapnic hypoxia). The main focus is on the mechanisms and signaling pathways involved in the formation of ischemic tolerance in the brain during intermittent hypercapnic hypoxia. Importantly, the combined effect of hypoxia and hypercapnia exerts a more pronounced neuroprotective effect compared to their separate application.
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