Publications by authors named "Okonska Maja"
T regulatory lymphocytes (Treg) expressing CCR5 exhibit strong suppression activity in various autoimmune disorders. However, there remains a lack of comprehensive understanding regarding their involvement in the development of type 1 diabetes (T1D). In this study, we examined the role of the CCR5/CCL5 axis in regulating inflammatory response and its impact on regulatory T cells in type 1 diabetes (T1D).
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- An 11-year-old girl with multihormonal pituitary deficiency, previously treated for a brain tumor, experienced excessive daytime sleepiness after starting recombinant growth hormone (rGH) therapy at age 10.
- Despite extensive testing showing no significant issues, she was later found to have massive tonsillar hypertrophy causing obstructive sleep apnea.
- After undergoing adenotonsillectomy, her symptoms significantly improved, highlighting the need for regular laryngologist evaluations for children on rGH therapy to monitor potential airway issues.
Introduction: Craniopharyngioma (CP) is a tumor, which damages pituitary function because of its localization. Panhypopituitarism (PHP) and excessive weight gain with lipid dysfunction are frequently observed. The growth hormone therapy (rGH) profits in the increase of growth rate and also may have metabolic effects like body weight reduction.
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