Antiplasmodial Potentials, Phytocompounds and the Possible Toxic Effects of Administration of Ethylacetate Extract of Spondias mombin Linn.

Malaria, caused by Plasmodium parasites, is a global health concern. Natural products, such as plant extracts, are investigated for new antimalarial agents. Spondias mombin, traditionally used for medicinal purposes, was examined for its effects on parasitemia, haematological parameters, antioxidant activities, liver function biomarkers, and serum electrolytes in Plasmodium berghei-infected mice.

Process optimization, scale-up studies, economic analysis and risk assessment of phenolic rich bioactive extracts production from L. leaves via heat-assisted extraction technology.

This work investigated the influence of process variables of extraction temperature (35-55 °C), solid to liquid ratio (1:20-1:50 g/mL) and time (100-200 min) on the total phenolic content (TPC) and yield (EY) of leaves (CPL) extracts using Box-Behnken experimental design available in Design Expert software. Bi-objective process optimization was also carried out using the desirability function algorithm. The optimum process variables were later used to design an integrated process for the production of CPL extracts with the assistance of SuperPro Designer software.

Heterogeneously catalyzed biodiesel production from Azadiricha Indica oil: Predictive modelling with uncertainty quantification, experimental optimization and techno-economic analysis.

This study presents predictive modelling with uncertainty analysis, optimization and techno-economic feasibility of Bio-catalyzed Biodiesel Production from Azidirica Indica Oil (BCBPAIO). Central Composite Design (CCD) predictive model and optimum conditions for BCBPAIO were developed in Design Expert software. The model uncertainty analysis was performed using Monte Carlo simulation.

Black-box modelling, bi-objective optimization and ASPEN batch simulation of phenolic compound extraction from root.

root (NLR) extract is one of phytochemicals used to treat various ailments in most of developing countries. This investigation focuses on modelling, optimization and computer-aided simulation of phenolic solid-liquid extraction from NLR. The extraction experiments were conducted at extraction temperature (ET: 33.

Process optimization for simultaneous production of cellulase, xylanase and ligninase by SCPW 17 under solid state fermentation using Box-Behnken experimental design.

Multienzyme complex has attracted increased attention in biofuel technology. They offer solutions to effective degradation of complex plant material into fermentable sugars. Microorganisms, especially bacteria and fungi, are well studied for their ability to produce enzymes complex unlike yeast.

Citraconylation and maleylation on the catalytic and thermodynamic properties of raw starch saccharifying amylase from .

Amylase capable of raw starch digestion presents a cheap and easier means of reducing sugar generation from various starch sources. Unfortunately, its potential for use in numerous industrial processes is hindered by poor stability. In this work, chemical modification by acylation using citraconic anhydride (CA) and maleic anhydride (MA) was used to stabilize the raw starch saccharifying amylase from .

Patient-Specific Surgical Implants Made of 3D Printed PEEK: Material, Technology, and Scope of Surgical Application.

Additive manufacturing (AM) is rapidly gaining acceptance in the healthcare sector. Three-dimensional (3D) virtual surgical planning, fabrication of anatomical models, and patient-specific implants (PSI) are well-established processes in the surgical fields. Polyetheretherketone (PEEK) has been used, mainly in the reconstructive surgeries as a reliable alternative to other alloplastic materials for the fabrication of PSI.

Chemical modification with phthalic anhydride and chitosan: Viable options for the stabilization of raw starch digesting amylase from Aspergillus carbonarius.

The raw starch digesting type of amylase (RSDA) presents greater opportunities for process efficiency at cheaper cost and shorter time compared to regular amylases. Chemical modification is a simple and rapid method toward their stabilization for a wider application. RSDA from Aspergillus carbonarius was modified with either phthalic anhydride (PA) or chitosan.

Structural and spectroscopic characterisation of a heme peroxidase from sorghum.

A cationic class III peroxidase from Sorghum bicolor was purified to homogeneity. The enzyme contains a high-spin heme, as evidenced by UV-visible spectroscopy and EPR. Steady state oxidation of guaiacol was demonstrated and the enzyme was shown to have higher activity in the presence of calcium ions.

Stabilization of a raw starch digesting amylase from Aspergillus carbonarius via immobilization on activated and non-activated agarose gel.

Applications of raw starch digesting amylases (RSDAs) are limited due to instability, product inhibition of enzyme and contamination. RSDA from Aspergillus carbonarius was stabilized through immobilization on agarose gel by adsorption, spontaneous crosslinking and conjugation using glycidol, glutaraldehyde or polyglutaraldehyde. Effects of immobilization on kinetics, catalytic, storage and operational stability of immobilized enzyme were evaluated.

Stabilization of a raw-starch-digesting amylase by multipoint covalent attachment on glutaraldehyde-activated amberlite beads.

Raw-starch-digesting enzyme (RSDA) was immobilized on Amberlite beads by conjugation of glutaraldehyde/ polyglutaraldehyde (PG)-activated beads or by crosslinking. The effect of immobilization on enzyme stability and catalytic efficiency was evaluated. Immobilization conditions greatly influenced the immobilization efficiency.

Raw starch digesting amylase from Thermoactinomyces thalpophilus F13.

Thermoactinomyces thalpophilus produced a raw-starch digesting amylase (RSDA) when grown on both cereal and tuber starches. Glucose, maltose and glycerol repressed enzyme production. Highest activity was recorded on rice starch (39 U ml(-1)).

Microbial contaminants of commercially bottled non-alcoholic drinks produced in Nigeria.

When microbiological analyses were conducted on 90 samples of soft drinks representing 30 different products commercially available in Nigeria, contaminants were detected in 50% of them. The isolates were mainly saprophytic and non-pathogenic: Bacillus spp. (35%), Lactobacillus spp.