In silico medicine and -omics strategies in nephrology: contributions and relevance to the diagnosis and prevention of chronic kidney disease.

Chronic kidney disease (CKD) has been increasing over the last years, with a rate between 0.49% to 0.87% new cases per year.

Uncovering the Drivers of Childhood Immunization Inequality with Caregivers, Community Members and Health System Stakeholders: Results from a Human-Centered Design Study in DRC, Mozambique and Nigeria.

Background: The importance of immunization for child survival underscores the need to eliminate immunization inequalities. Few existing studies of inequalities use approaches that view the challenges and potential solutions from the perspective of caregivers. This study aimed to identify barriers and context-appropriate solutions by engaging deeply with caregivers, community members, health workers, and other health system actors through participatory action research, intersectionality, and human-centered design lenses.

Effects of Postpartum Family Planning Counselling on Contraceptives Knowledge, Attitude and Intention Among Women Attending a General Hospital in The Gambia: A Randomized Controlled Trial.

Purpose: This study aimed to evaluate the effectiveness of PPFP counselling on contraceptives knowledge, attitudes and intention among women attending a general hospital in The Gambia.

Materials And Methods: A quasi-experimental design with an intervention and comparison group was used. The intervention was PPFP counselling using the GATHER approach.

SARS CoV-2 Seroprevalence in Selected States of High and Low Disease Burden in Nigeria.

Importance: The global impact of COVID-19 has led to an increased need to continuously assess disease surveillance tools. The utility of SARS-CoV-2 serologic tools in determining immunity levels across different age groups and locations in helping to quickly assess the burden of COVID-19 with significant health policy implications is unknown.

Objective: To determine the prevalence of SARS-CoV-2 antibodies with respect to the age group and sex of participants.

Prevalence, Pattern and Predictors of Elder Abuse in Benin City, Edo State, Nigeria: An Urban and Rural Comparison.

Background: Elder abuse is a growing concern globally and the consequences can be detrimental to the wellbeing of the elderly. In Nigeria, it is a hidden problem, under-reported with limited national response. This study compared the prevalence and pattern of elder abuse and its determinants between urban and rural communities in Benin-City.

Knowledge and Skills of Health Care Workers Implementing Integrated Maternal, Newborn and Child Health Strategy in Edo State, Nigeria.

Background: The Integrated Maternal, Newborn and Child Health (IMNCH) strategy which advocates for integrated care of mother and newborn requires skilled health care workers (HCWs) for effective implementation. This study assessed the capacity of HCWs in Primary Health Care (PHC) facilities in Edo State to implement the IMNCH strategy.

Methods: This cross-sectional study involved 333 HCWs drawn from PHC facilities in Edo State using multistage sampling technique.

Hypertension and Alcohol: A Mechanistic Approach.

Hypertension is a global public health challenge and a major cause of morbidity and mortality. Alcohol is one of the most frequently abused substances around the world. The financial implications of treating hypertension are also significant.

Artificial Intelligence: Is It Armageddon for Breast Radiologists?

Artificial Intelligence (AI) has taken radiology by storm, in particular, mammogram interpretation, and we have seen a recent surge in the number of publications on potential uses of AI in breast radiology. Breast cancer exerts a lot of burden on the National Health Service (NHS) and is the second most common cancer in the UK as of 2018. New cases of breast cancer have been on the rise in the past decade, while the survival rate has been improving.

Ectopic pregnancy at the Lagos University Teaching Hospital, Lagos, South-Western Nigeria: Temporal trends, clinical presentation and management outcomes from 2005 to 2014.

Background: There is uncertainty in the trend of ectopic pregnancy incidence in the Southwest region, though the region has a lower fertility rate and a higher contraceptive use than some other regions of Nigeria. The study objective was to determine the temporal trends, presentation and management outcome of ectopic pregnancy at the Lagos University Teaching Hospital (LUTH), Lagos, South-Western Nigeria over a decade.

Subjects And Methods: This is a retrospective study of ectopic pregnancies at LUTH, Lagos, Nigeria, from January 2005 to December 2014.

How to Read, Write, and Review the Imaging Literature.

Everyone at all levels in academic radiology is supposed to know how to read an original research article or a review article and to evaluate it critically, to participate in writing such manuscripts, and, as one becomes more senior, to participate in the peer review process, yet there is little formal teaching in our experience as to how to do these inter-related activities throughout radiology training. The purpose of this review article is therefore to provide our perspective - from the junior trainee to the senior radiology attending - as to how one should be reading, reviewing, and writing the imaging literature, and also providing guidance from other thought leaders in this area, and from the literature itself. We hope to inspire radiology trainees and radiologists at all levels, particularly those in academic careers, to more fully participate in peer review and in radiology publication.

Knowledge, Attitude and Preventive Practices Against Lassa Fever Among Residents in a Rural Community in Southern Nigeria.

Background: Lassa fever is of significant public health concern due to the high morbidity and mortality associated with the disease. There is need for the general public, especially those in the rural communities, to have adequate knowledge of Lassa fever as well as engage in proper measures that will prevent the occurrence of future outbreaks.

Objective: To assess the knowledge, attitude and preventive practices against Lassa fever of adult residents among a rural community in Edo State, Nigeria.

Premarital sex and condom use among trainee healthcare workers: an exploratory study of selected healthcare training institutions in Enugu State, Nigeria.

Introduction: To assess the prevalence and causes of premarital sex and condom use among trainee healthcare workers in selected healthcare institutions in Enugu State, Nigeria; and to proffer solution to challenges identified.

Methods: We used a mixed study approach with qualitative and quantitative components. Informed consent was obtained from participants and data collected using self-administered structured questionnaires.

Fetal Congenital Anomaly in Tertiary Hospital in Lagos, South-West Nigeria: A Review of Presentation and its Outcome.

Background: Congenital Anomalies are a major contributor to perinatal deaths worldwide. The World Health Organization (WHO) estimates that 303,000 newborns die within the first 4 weeks of life worldwide as a result of it. The exact cause is often difficult to determine and as such efforts are geared towards prevention AIM AND OBJECTIVE: This study was done to determine the common presentations as well as epidemiological features of pregnant women with anomalous fetus and at the Lagos University Teaching Hospital.

Maternal serum vitamin D levels and preterm delivery among low-risk parturients in Lagos, Nigeria.

Objective: To determine the association between low maternal vitamin D levels and preterm delivery among parturients in Lagos, Nigeria.

Methods: The present study was an analytical cross-sectional study of women with preterm deliveries (defined as <37 weeks) and women with term deliveries (defined as ≥37 weeks) at the labor unit of Lagos University Teaching Hospital between December 1, 2015, and October 31, 2016. Relevant information was obtained via a proforma, and maternal venous samples were collected immediately after delivery.

Giant cell myocarditis causing refractory ventricular tachycardia in a pediatric patient.

Giant cell myocarditis should be considered in all pediatric patients with refractory ventricular arrhythmia. Endomyocardial biopsy should be obtained to confirm the diagnosis of giant cell myocarditis.

Assessment of the performance of community-directed treatment with ivermectin strategy for the control and elimination of onchocerciasis in Edo State, Nigeria.

Background: Community-directed treatment with ivermectin (CDTI) was developed in the mid 1990's as a solution for the control and elimination of onchocerciasis. It requires that ivermectin be administered continuously over a period of at least 14 years with community involvement before elimination can be achieved.

Objectives: The objective of this study is to assess the performance of CDTI strategy for control and elimination of onchocerciasis in endemic Local Government areas of Edo State.

Peripartum hysterectomy in a Nigerian university hospital: An assessment of severe maternal outcomes with the maternal severity index model.

Background: Peripartum hysterectomy is life-saving and a life-threatening criterion of the World Health Organization (WHO) maternal near-miss concept. The maternal severity index (MSI) model was developed to assess the outcome of severe maternal morbidities. This study assessed severe maternal outcomes of peripartum hysterectomy using the MSI model and related maternal severity score with mortality.

What experts think about integrating mobile health into routine immunization service delivery in Nigeria.

Background: Routine immunization (RI), like other essential health services, could benefit from mobile telephony and especially from the current trend of their increased use in health service delivery. SMS text messages have been recorded to be highly effective in many settings around the world and could be used for reminders and recalls to improve RI performance in Nigeria. This qualitative study assessed the state of RI services, obtained expert opinion on integration of mobile health (mHealth) into RI, and also identified potential threats to such an initiative.

Dental care knowledge and practice of a group of health workers in benin city, Nigeria.

Background: The correlation between knowledge of dental care knowledge and its practice varies among the different health professionals.

Aim: The aim of the following study is to assess the knowledge and practice of health workers in a private medical health facility on dental care.

Subjects And Methods: A descriptive cross-sectional study was carried out on the health workers in Faith Medical Center, Benin City, Nigeria.

Lung function indices of flour millworkers in Edo and Delta States.

Unlabelled: AIMS AND OBJECTIVES Flour dust has been associated with lung function impairment and Chronic Obstructive Airway Disease (COAD) among grain workers. This study was therefore conducted to assess the lung function indices of flour mill workers in Edo and Delta states, of Nigeria. MATERIALS AND METHODS Comparative cross-sectional study designed was utilized for the study and it was carried out over a period of six months, (Nov 2010 to May 2011) among 200 flour mill workers and 200 hospital workers in Edo and Delta states.

Epidemiology of pulmonary tuberculosis in University of Benin Teaching Hospital and Central Hospital, Benin City.

Background: Poverty, overcrowding, homelessness, malnutrition and the AIDS pandemic has worsen the problem of tuberculosis in the developing countries, Nigeria inclusive with Nigeria being the fifth among the twenty-two high tuberculosis burden countries.

Objective: To identify the epidemiological factors associated with the distribution of tuberculosis in Benin City, Nigeria.

Methods: This study was a cross-sectional and descriptive one and carried out in two major public hospitals in Benin City, Nigeria, namely University of Benin Teaching Hospital (a tertiary hospital) and the Central Hospital (a secondary hospital) within one year period.

Knowledge attitude and practice about breast cancer among civil servants in Benin City, Nigeria.

Background: Breast cancer is often associated with severe morbidity and mortality especially when the patients present late. A major reason why patients present late is the lack of awareness about breast cancer, its complications and the management.

Methods: The study was carried out using a structured questionnaire.

An epidemiological study of football (soccer) injuries in Benin City, Nigeria.

Background: The increase in popularity of soccer and expectations from players make significant numbers of soccer injuries conceivable. Concerns have been expressed about the demand placed on the modern-day footballer and translation of these physical and mental demands into injuries. Despite the popularity and importance of the game of soccer in Benin, no detailed study on the occurrence of soccer injury has been carried out.

Prevalence of pterygium and pingueculum among motorcyclists in Nigeria.

Objectives: To find out the prevalence of pingueculum and pterygium among commercial motorcyclists in Benin City, Nigeria and to note any associated or risk factors.

Design: A prospective, cross sectional, case control study.

Setting: A local Government Area (Oredo) and University of Benin Teaching Hospital, Benin City, Nigeria.

Awareness of high blood pressure status, treatment and control in a rural community in Edo State.

A cross-sectional study was carried out in Udo, a rural community in Ovia South-west LGA of Edo State to assess the level of awareness of high blood pressure status, treatment and control. Cluster sampling method was used to select participants and data collection was by researcher administered questionnaire. Blood pressure measurement was by standardized method.