Publications by authors named "Okita Yutaka"

Article Synopsis
  • A study analyzing the surgical treatment of aortoesophageal fistula (AEF) from 2020 to 2021 in Japan revealed that 61% of cases were secondary AEF, often arising from previous aortic surgeries.
  • Among 123 patients, the operative mortality rate was 18.7%, with significant factors contributing to mortality including postoperative complications like bleeding, stroke, and pneumonia.
  • The findings highlight the need for improved treatment strategies for AEF, as both surgical methods (open repair and TEVAR) were linked to high mortality rates and specific risk factors like dyslipidemia.
View Article and Find Full Text PDF

Objectives: The mechanisms behind the onset of acute aortic dissection have not been fully elucidated. We developed dynamic synchrotron-based X-ray phase-contrast tomography to quantitatively study the dynamics of biological samples and applied it to the fresh aortic wall in acute type-A aortic dissection (ATAAD).

Methods: Fresh, ring-shaped aortas undergoing aortic repair in ATAAD were measured in a container filled with normal cold saline within 24 h of surgery.

View Article and Find Full Text PDF

We reported our long-term results of valve sparing aortic root replacement (VSRR) and aortic cusp repair for aortic regurgitation( AR) were satisfactory. Three hundred twenty-seven patients had VSRR, and 164 patients of them had aortic cusp repair for prolapse. At 10 years after the operation, the overall survival was 91.

View Article and Find Full Text PDF

Stroke and intracranial hemorrhage (ICH) are serious complications that are difficult to manage during surgery for active infectious endocarditis (AIE). Relevant society guidelines still recommend delaying the cardiac surgery for AIE with ICH for 4 weeks. Some early studies indicated that the mortality rate decreases when cardiac surgery for ICH is delayed.

View Article and Find Full Text PDF

Objectives: The management of aortic arch disease is complex. Open surgical management continues to evolve, and the introduction of endovascular repair is revolutionizing aortic arch surgery. Although these innovative techniques have generated the opportunity for better outcomes in select patients, they have also introduced confusion and uncertainty regarding best practices.

View Article and Find Full Text PDF

The patient is a 56-year-old man. He fell while playing golf and sustained a contusion on his right chest. He fell into hemorrhagic shock during surgery for a right clavicle fracture at a nearby hospital and required cardiac resuscitation.

View Article and Find Full Text PDF

Objective: To clarify the current status of surgical treatment of acute aortic dissection (AAD) in Japan through the Japan Cardiovascular Database analysis.

Methods: In total, 7194 patients who underwent surgical treatment for AAD in 2021, including type A (TAAAD) (n = 6416) and type B (TBAAD) (n = 778), were investigated.

Results: The median age was 70 years, with patients older than age 80 years constituting 21.

View Article and Find Full Text PDF

Background: Purulent pericarditis is rare in the modern era of antibiotics. However, it is a rapidly progressive, life-threatening disease with complications, including cardiac tamponade and left ventricular pseudoaneurysm.

Case Summary: A 44-year-old female was admitted with a pontine haemorrhage.

View Article and Find Full Text PDF

This study retrospectively evaluated the mid-term outcomes of surgical aortic valve replacement (SAVR) using a stented porcine aortic valve bioprosthesis (Mosaic; Medtronic Inc., Minneapolis, MN, USA) with concomitant mitral valve (MV) repair. From 1999 to 2014, 157 patients (median [interquartile range] age, 75 [70-79] years; 47% women) underwent SAVR with concomitant MV repair (SAVR + MV repair), and 1045 patients (median [interquartile range] age, 76 [70-80] years; 54% women) underwent SAVR only at 10 centers in Japan as part of the long-term multicenter Japan Mosaic valve (J-MOVE) study.

View Article and Find Full Text PDF

Background: Long-term results of valve-sparing aortic root replacement (VSRR) and aortic cusp repair for aortic regurgitation are unclear.

Methods: VSRR by reimplantation was performed in 363 patients. Tricuspid aortic valve (TAV) and bicuspid aortic valve were found in 285 and 71 patients, respectively.

View Article and Find Full Text PDF
Article Synopsis
  • - The study aimed to create clinical guidelines for managing vascular Behçet's disease (BD) through the collaboration of a task force and the Japanese Ministry of Health.
  • - After generating clinical questions and refining recommendations through multiple rounds of review, the study produced 17 guidelines covering diagnosis, disease assessment, and treatment strategies.
  • - The guidelines emphasize the use of immunosuppressive treatments and anticoagulation for specific cases, along with algorithms for diagnosing and treating arterial and venous involvement in BD.
View Article and Find Full Text PDF

turns 30 in 2023. A historical review since it was first published in March 1993 is presented.

View Article and Find Full Text PDF

Background: Three-dimensional aortic root evaluation using virtual reality (VR) techniques for valve-sparing aortic root replacement (VSARR) preparation has not yet been implemented, so we demonstrated VR computed tomography (VR-CT) and assessed its utility for VSARR.

Methods and results: We enrolled 72 patients who underwent multidetector CT before elective VSARR for annuloaortic ectasia with tricuspid aortic valve. The geometries of their aortic roots were measured with a VR-CT workstation.

View Article and Find Full Text PDF

Objective: Reporting clinical outcomes of acute type A aortic dissection.

Methods: Data derived from the survey of the Japanese Association for Thoracic Surgery, the Japan Cardiovascular Database, and the Japanese Registry of All Cardiac and Vascular Diseases were analyzed.

Results: Between 2012 and 2015, the Japanese Registry of All Cardiac and Vascular Diseases study collected 13,131 patients and the hospital mortality was 24.

View Article and Find Full Text PDF

Background: Bicuspid aortic valve (BAV) is the most frequent congenital cardiac anomaly. We report a successful case in which the tricuspidization technique with valve-sparing aortic root replacement was used for BAV with severe aortic regurgitation.

Case Presentation: A 22-year-old man was admitted for progressively worsening aortic regurgitation due to a congenital BAV.

View Article and Find Full Text PDF

Objectives: The goal of this study was to evaluate the fate of the downstream aorta following total arch replacement.

Methods: Between October 1999 and March 2018, a total of 740 patients underwent total arch replacement. After excluding connective tissue disease, previous descending or thoracoabdominal aortic surgery, patients without adequate preoperative images or operative mortality, late outcomes consisting of additional surgery for distal dilation and distal aortic events were evaluated in 623 survivors (240 aortic dissections, including 139 patients with acute dissection and 383 with a non-dissection aneurysm).

View Article and Find Full Text PDF

Background: Kinking or iatrogenic stenosis in the frozen elephant trunk (FET) is a possible complication, however, there have been few cases reported.

Case Description: A 43-year-old male with acute type A aortic dissection (ATAAD) underwent total arch replacement and FET installation. After weaning from the cardiopulmonary bypass, both femoral pulses were absent.

View Article and Find Full Text PDF

Background: It remains unclear whether the Rho-kinase (ROCK) inhibition in combination with mechanical circulatory support (MCS) had a synergic protective effect on myocardial ischemia (MI)/reperfusion injury in therapeutic strategies for acute myocardial infarction (AMI). We report the results of an approach using a rat model consisting of a miniaturized cardiopulmonary bypass (CPB) and AMI.

Methods: A total of 25 male Wistar rats were randomized into 5 groups: (1) Sham: a suture was passed under the left anterior descending artery (LAD) creating no MI.

View Article and Find Full Text PDF

Our current approach towards total arch replacement includes the following: (1) innominate vein mobilization, (2) no neck vessel taping, and no dissection of the vagal nerve, (3) meticulous selection of arterial cannulation site and type of arterial cannula, (4) antegrade cerebral perfusion(ACP)for neuro-protection, utilizing three balloon-tipped cannular from inside the arch, (5) whole-body hypothermia with minimal tympanic temperatures between 20 and 23 °C and minimal rectal temperatures below 30 °C, (6) distal enucleation and felt reinforcement for in zone III distal anastomosis using four branched graft, (7) early re-warming after distal anastomosis with ACP flow adjustment while monitoring brain oxygenation by near-infrared spectroscopy (NIRS) and (8) second anastomosis is proximal and last one is arch vessel reconstruction, (9) maintaining strict fluid balance below 1000 ml by the extracorporeal ultrafiltration method (ECUM) during cardiopulmonary bypass (CPB), with the expectation of more rapid pulmonary functional recovery.

View Article and Find Full Text PDF