Blood glucose level and lipid profile of alloxan-induced hyperglycemic rats treated with single and combinatorial herbal formulations.

The current study sought to investigate the capacities of single and combinatorial herbal formulations of leaf extracts of Acanthus montanus, Asystasia gangetica, Emilia coccinea, and Hibiscus rosasinensis to reverse hyperglycemia and dyslipidemia in alloxan-induced diabetic male rats. Phytochemical composition of the herbal extracts, fasting plasma glucose concentration (FPGC), and serum lipid profile (SLP) of the rats were measured by standard methods. The relative abundance of phytochemicals in the four experimental leaf extracts was in the following order: flavonoids > alkaloids > saponins > tannins.

Radical scavenging potentials of single and combinatorial herbal formulations in vitro.

Reactive oxygen and nitrogen species (RONS) are involved in deleterious/beneficial biological processes. The present study sought to investigate the capacity of single and combinatorial herbal formulations of Acanthus montanus, Emilia coccinea, Hibiscus rosasinensis, and Asystasia gangetica to act as superoxide radicals (SOR), hydrogen peroxide (HP), nitric oxide radical (NOR), hydroxyl radical (HR), and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical antagonists using in vitro models. The herbal extracts were single herbal formulations (SHfs), double herbal formulations (DHfs), triple herbal formulations (THfs), and a quadruple herbal formulation (QHf).

Comparative hypoglycemic activities of aqueous and ethanolic extracts of four medicinal plants (Acanthus montanus, Asystasia gangetica, Emilia coccinea and Hibiscus rosasinensis) in Type I diabetic rats.

Background: The present study ascertained the capacities of crude aqueous and ethanolic leaf extracts of Acanthus montanus (ACMO), Asystasia gangetica (ASGA), Emilia coccinea (EMCO), and Hibiscus rosasinensis (HIRO), as well as their combinatorial formulations to ameliorate hyperglycemia in Type I diabetic rats.

Materials And Methods: Hyperglycemia was induced by single intraperitoneal injection of alloxan monohydrate in phosphate buffer saline (PBS) solution (pH = 7.4) dosage = 120 mg/kg; bw.

Cyanide and Aflatoxin Loads of Processed Cassava (Manihot esculenta) Tubers (Garri) in Njaba, Imo State, Nigeria.

Objectives: The present study sought to investigate the role of palm oil, in conjunction with the duration of fermentation, on cyanide and aflatoxin (AFT) loads of processed cassava tubers (Garri).

Materials And Methods: Matured cassava (Manihot esculenta Crantz) tubers were harvested from three different locations (Akunna, Mkporo-Oji and Durungwu) in Njaba Local Government Area, Imo State, Nigeria. The cassava tubers were processed into Garri according to standard schemes with required modifications and measured for cyanide content using titrimetric methods.

The proximate, mineral, and toxicant compositions of four possible food security crops from southeastern Nigeria.

The proximate, nutritional, and antinutritional compositions of the raw, cooked, and roasted samples of four Nigerian indigenous seeds-Sphenostylis stenocarpa, Pentaclethra macrophylla, Mucuna flagellipes, and Citrullus colocynthis-were evaluated. Also estimated were zinc and divalent cation bioavailability of the seeds using millimolar ratios/kg dry weight of [calcium]/[phytate], [phytate]/[zinc], [calcium][phytate]/[Zn], and [phytate]/[total phosphorus]. The results obtained revealed that the seeds of P.