Anti-plasmodial and anti-inflammatory activities of cyclotide-rich extract and fraction of (R. & S.) D.C. ().

Background: , commonly called '', a versatile plant used locally to treat malaria fever in some parts of sub-Saharan Africa was investigated for anti-plasmodial and anti-inflammatory activities.

Objective: The study was designed to evaluate the antiplasmodial as well as anti-inflammatory activities of whole extract and cyclotide-rich fraction of .

Method: The dichloromethane-methanol extract (ODE) of the plant, was investigated for suppressive and curative antiplasmodial activities against in mice.

Herb-drug interaction between the extract of Hibiscus sabdariffa L. and hydrochlorothiazide in experimental animals.

Decoctions of Hibiscus sabdariffa L. (Family Malvaceae) are very popular for the preparation of homemade refreshing drinks and are also used medicinally for a variety of ailments. Particularly remarkable are the various scientific reports supporting diuretic and antihypertensive potentials.