Effect of Moderate Intensity Continuous Training and Slow Type Interval Training to Gene Expression of TGF-β in Type 2 Diabetes Mellitus Model Wistar Rats.

Background: Physical exercise is a process of increasing contraction of skeletal muscles involving several organ systems to increase energy formation and it is one of the pillars for the management of type 2 diabetes mellitus (TDM2). T2DM affects the expression of the TGF-β gene.

Objective: This study aims to determine the effect of moderate intensity continuous training and slow interval training in expression of TGF-β gene in wistar rats T2DM model.

Comparison of Gambier Extract (Uncaria Gambier Robx) and Angiotensin Receptor Blocker on Proteinuria Reduction and Antioxidants - Enhancement in Nephrotic Rat Models.

Background: Proteinuria is a significant clinical manifestation that causes edema in several diseases, including Nephrotic Syndrome (NS). Untreated proteinuria is strongly linked to the progression of kidney failure. One of the adjuvant therapies could be used to reduce proteinuria such as Angiotensin Receptor Blocker (ARB) including Losartan®.

Oxidative stress markers in initial therapy and remission of nephrotic syndrome and serum malondialdehyde level predictor from routine laboratory test.

Aim To compare oxidative stress state of children with nephrotic syndrome at the first week of treatment and in remission, and to predict malondialdehyde (MDA) level from routine laboratory tests. Methods This cross-sectional study involved 80 1-18 years old children with nephrotic syndrome, who were divided into two groups: initial group (40 children in the first week of therapy) and remission group (40 children in remission). Demographic characteristics of the patients were taken by a questionnaire.

Risk Factors for Catheter-Associated Urinary Tract Infection and Uropathogen Bacterial Profile in the Intensive Care Unit in Hospitals in Medan, Indonesia.

Aim: To evaluate the risk factors of CAUTI in ICU patients at Haji Adam Malik General Hospital and Universitas Sumatera Utara Hospital, Medan, Indonesia.

Methods: This hospital-based observational research was an observational analytic research with a cross-sectional study. This research was conducted at Haji Adam Malik General Hospital Medan, Universitas Sumatera Utara Hospital, and Department of Microbiology Medical Faculty of Medicine Universitas Sumatera Utara, on July to August 2018 until the number of samples was fulfilled.

Impact of the rs35753505 C/T Polymorphisms on Neuregulin 1 Levels in Preterm Infants.

Background: Neuregulin (NRG) 1 plays an important role in the development of various organ systems in human. Single nucleotide polymorphisms rs35753505 C/Tof the gene encoding NRG1 evident as allele C and T with genotypes of CT, CC, and TT are believed to have an impact on NRG1 levels.

Aim: To determine the impact of the NRGrs35753505 C/T polymorphisms on NRG1 levels in preterm infants.

Mean Blood Pressure Difference among Adolescents Based on Dyssomnia Types.

Background: Dyssomnia is the most frequent sleep disturbance and associated with increased blood pressure. There has been no study determining the difference in mean blood pressure based on dyssomnia types among adolescents.

Objective: To determine the difference in mean blood pressure among adolescents based on dyssomnia types.