Toxicity assessment of watermelon seed supplemented diet in rats.

Health benefits have been attributed to the consumption of watermelon ( L.) seeds in sub-Saharan Africa and Asia but the potential toxicity especially on chronic use remains to be investigated. Here, diets containing watermelon seeds (WMSs) at 2.

Development of multiepitope subunit protein vaccines against using an immunoinformatics approach.

Approximately one-third of the world's human population is estimated to have been exposed to the parasite . Its prevalence is reportedly high in Ethiopia (74.80%) and Zimbabwe (68.

Anticholinergic Drug Burden Tools/Scales and Adverse Outcomes in Different Clinical Settings: A Systematic Review of Reviews.

Background: Cumulative anticholinergic exposure (anticholinergic burden) has been linked to a number of adverse outcomes. To conduct research in this area, an agreed approach to describing anticholinergic burden is needed.

Objective: This review set out to identify anticholinergic burden scales, to describe their rationale, the settings in which they have been used and the outcomes associated with them.

The microstructural effects of aqueous extract of Garcinia kola (Linn) on the hippocampus and cerebellum of malnourished mice.

Objective: To assess the neuroprotective effects of aqueous extract of Garcinia kola on neurotoxin administered malnourished mice adopting histological procedure.

Methods: The study was carried out using thirty-two adult malnourished mice which were randomly assigned into four groups (n=8): A, B, C and D. Group A served as control, while the other groups served as the experimental groups.

Microanatomical effects of ethanolic extract of Cola nitida on the stomach mucosa of adult Wistar rats.

The study investigated the microanatomical effects of the extracts of Cola nitida on the stomach mucosa of adult male Wistar rats. Twenty adult male wistar rats were randomly divided into four equal groups of A, B, C and D (n = 5). Animals in experimental groups B, C and D were given 600 mg/kg body weight of crude extract of Cola nitida each by oral intubation for five, seven and nine consecutive days respectively, while group A (control) received equivalent volume of distilled water.

Renal distal tubular secretory mechanisms in healthy Nigerian subjects.

The distal tubular secretory mechanisms of 30 healthy Nigerians were investigated. This entailed the collection of three different 24 hour urine samples; firstly basal values, secondly during the administration of 15 g of NH4Cl and finally when 5 g of KCl was given addition to 15 g NH4Cl. The basal 24 hour urinary volume was 1.

Renal excretion of fluid, electrolytes and hydrogen ions before and during diamox administration in healthy Nigerians.

Twenty-four urine specimens of eleven healthy Nigerians taken during the cool rainy season, were examined before and during diamox (acetazolamide) administration. Mean control volume-output was 1.4 litres containing 109.

The pathogenesis of endomyocardial fibrosis: the question of 5-hydroxytryptamine.

Thirty Nigerians with established endomyocardial fibrosis were studied. Basal serum 5-hydroxytryptamine levels were estimated on three different occasions at one-monthly intervals. Twentyfour hours before each estimation, dietary staples containing 5-hydroxytryptamine were excluded from the diet.