Publications by authors named "Ojewuyi A"

Introduction: Oritavancin is a semi-synthetic lipoglycopeptide antibiotic primarily used to treat serious infections caused by Gram-positive bacteria. The aim of this study was to elucidate possible molecular targets of oritavancin in human and microbes in relevance to its mechanism of action and model its pharmacokinetics for optimal dose selection in clinical practice.

Methods: Computational methods were used in this study which include target prediction, molecular docking, molecular dynamics simulation, pharmacokinetics prediction, and physiological-based pharmacokinetics (PBPK) modeling.

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Purpose: We described our experience in the management of PUV at UNIOSUN Teaching Hospital, Osogbo, Osun State.

Methods: This was a retrospective analysis of patients with diagnosis of PUV carried out over a 4 year period (2019-2023). Demographic characteristics, clinical presentation, diagnosis and mode of therapeutic interventions were the variables analysed.

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Background And Objectives: An appropriately balanced specialty distribution in residency training will ensure adequate coverage and delivery of essential health needs to the people. An understanding of the factors which influence doctors' career choices is important for all those involved in the training of Resident doctors. The aim of this study is to examine the factors influencing the Resident Doctors' choice of specialty.

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Background: Malaria is a parasitic disease of public health concern especially among children because of their vulnerability. Objective: The study sought to evaluate the prevalence and severity of malaria and to assess the factors associated with malaria parasitaemia among children.

Methods: This was a hospital-based cross-sectional observation study.

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