Publications by authors named "Oiwoh Sebastine Oseghae"
To investigate epidemiology of and risk factors for laboratory-confirmed mpox during the 2022 outbreak in Nigeria, we enrolled 265 persons with suspected mpox. A total of 163 (61.5%) were confirmed to have mpox; 137 (84.
View Article and Find Full Text PDFRibavirin ampoule formulation remains a major challenge in managing Lassa fever disease. Lassa fever is an endemic viral hemorrhagic fever in the West Africa subregion, which has high-dose ribavirin as the standard of care. The high-dose therapy required makes the 200 mg/ml ampoule dosing of ribavirin a daunting task to administer, especially during disease outbreaks.
View Article and Find Full Text PDFThis study reviewed the current knowledge on the epidemiology, pathophysiology, clinical presentations, diagnosis, treatment, quality-of-life assessment and recent trends in androgenetic alopecia (AGA). Relevant articles on AGA from PubMed, Google Scholar, Medline and Scopus from 1950 to 2024 were obtained and scrutinized..
View Article and Find Full Text PDFBackground: Many anthropometric measures have been developed in the last two decades to evaluate cardiovascular health and disease. However, the relationship between these measures and blood pressure is not commonly explored among young population.
Objective: This study sought to explore the relationship between selected traditional and novel anthropometric metrics and blood pressure among young people as part of ThE profile of anthRopometRy And psyChosocial issuEs on campus (TERRACE) study.
Background: Research from sub-Saharan Africa that contributes to our understanding of the 2022 mpox (formerly known as monkeypox) global outbreak is insufficient. Here, we describe the clinical presentation and predictors of severe disease among patients with mpox diagnosed between Feb 1, 2022, and Jan 30, 2023 in Nigeria.
Methods: We did a cohort study among laboratory-confirmed and probable mpox cases seen in 22 mpox-treatment centres and outpatient clinics across Nigeria.
Article Synopsis
- There is very limited data about mpox (a disease) during pregnancy, with only 65 cases reported globally since 1958, and 59 of those in the current outbreak.
- Pregnant women are more vulnerable to severe illness due to changes in their bodies, and African women seem to be at higher risk for complications.
- There are many challenges in diagnosing and managing mpox in pregnancy in Africa, including patients hiding their travel history and a lack of medical resources, so more support is needed to help these countries.
Background: Hospital-based morbidity and mortality records reflect the health status of host communities. This helps policymakers and industry actors plan and allocate resources for health services, research, training, and development. This study aimed to determine the pattern and outcome of medical admissions in a Nigerian teaching hospital.
View Article and Find Full Text PDFBackground: Obesity among the youth is a major public health problem. Globally, the burden of obesity has been on the increase, particularly among young persons, with associated psychosocial issues. This study aimed to present the rationale and design of ThE profile of anthRopometRy And psyChosocial issuEs on campus (TERRACE) Study and as well report some preliminary findings obtained on the anthropometric and psychosocial profile of young persons in some tertiary institutions in Oyo State, Nigeria.
View Article and Find Full Text PDFArticle Synopsis
- A study explored Nigerian resident doctors' participation and views on scientific research, including the challenges they face.
- Conducted with 438 doctors, the results showed a strong male majority and highlighted that many had engaged in research but few had published, with significant barriers identified like funding and training gaps.
- The findings emphasize the need for better support and training to enhance research opportunities for resident doctors in Nigeria to improve publication rates.
(1) Background: leadership behaviour is a poorly explored phenomenon among early-career doctors (ECDs). Good leadership is vital in maximising the effective management of patients in a clinical setting. While a good number of studies, though with small sample surveys, have researched the role of leadership in clinical setting quantitatively, qualitative investigations are yet to be done in Nigeria.
View Article and Find Full Text PDFIdiopathic scrotal calcinosis: report of 2 cases, and review of pathogenesis and factors that determine patients' acceptance of surgical treatment.
Clin Cosmet Investig Dermatol
July 2018
Introduction: Idiopathic scrotal calcinosis is a benign and rare disease of the scrotal skin that presents as solitary or multiple asymptomatic calcified nodules in the absence of systemic disorders of calcium/phosphorus balance.
Case Reports: We report the management of 2 cases and review the literature with comments on factors that determine acceptance or otherwise of surgical treatment. Our patients were 29 and 33 years old and presented with nodular scrotal lesions.
Background: This study was conducted to determine the prevalence of hepatitis C virus antibody (anti-HCV), among a healthy university undergraduate population in south-western Nigeria.
Materials And Methods: Relevant medical information of students who underwent the post-admission screening exercise for the year 2012, at the Ladoke Akintola University of Technology (LAUTECH), Health Center, Ogbomoso were extracted from the laboratory log book. All tests were done using rapid anti-HCV test kit by Health - Chem diagnostics, USA.