Publications by authors named "Oi Alatise"
Background: Hemorrhoidectomy is considered as the most effective approach for patients with grade III and grade IV hemorrhoids; the operative procedure may be associated with significant postoperative pain and other complications. Several surgical techniques and devices have been developed to overcome these postoperative problems.
Objective: To compare perioperative and postoperative outcomes of hemorrhoidectomy performed with the LigaSure and the conventional Milligan-Morgan hemorrhoidectomy among Nigerian patients with symptomatic hemorrhoids.
Analysis of Risk Factors, Treatment Patterns, and Survival Outcomes After Emergency Presentation With Colorectal Cancer: A Prospective Multicenter Cohort Study in Nigeria.
J Surg Oncol
November 2024
Background And Objectives: Prospective data on presentation and outcomes of colorectal cancer (CRC) in Nigeria are limited; however, emergency presentation with advanced disease is thought common.
Methods: Consecutive CRC patients presenting at six sites over 6 years were included. Risk factors for emergency presentation were evaluated using logistic regression methods.
Article Synopsis
- In Nigeria, gastric cancer ranks as the 10th most common and 9th most deadly cancer, but there is limited data available to fully understand it.
- A study evaluated 138 patients diagnosed with gastric cancer over 15 years, finding that most patients presented with significant weight loss and anorexia, and many had advanced disease.
- Most patients received some form of treatment, with nearly half undergoing both chemotherapy and surgery, though over 50% were deceased by the time of follow-up, highlighting the need for improved data quality and timely interventions.
Article Synopsis
- - The study examines out-of-pocket costs for breast cancer treatment in Nigeria, highlighting that most patients face significant financial burdens, with a majority experiencing catastrophic health expenditures (CHE) due to the high costs of care.
- - Data was gathered from 71 patients undergoing treatment, revealing that 78.9% to 100% experienced CHE, as their healthcare costs often exceeded 40% of their ability to pay or set income thresholds, and most patients lacked health insurance.
- - The findings underscore the urgent need for policy changes to improve access to affordable cancer care in Nigeria, given that over 70% of patients at a major facility are financially strained by their treatment.
Article Synopsis
- Cholecystectomy and common bile duct exploration are frequent surgeries in Nigeria that can lead to complications like biliary tree injury and retained stones, necessitating repeat surgeries.
- A study at Obafemi Awolowo University Teaching Hospital examined the use of endoscopic retrograde cholangiopancreatography (ERCP) for managing these complications from March 2018 to April 2023, using various imaging techniques before the procedures.
- The study involved 72 ERCPs on 45 patients, with common issues like ascending cholangitis and retained stones, showcasing that ERCP was successful and reduced unnecessary surgeries, with recommendations for swift referrals in such cases.
Purpose: The incidence of GI cancers is increasing in sub-Saharan African countries. We described the oncological care pathway and assessed presentation, diagnosis, and treatment intervals and delays among patients with GI cancer who presented to the Obafemi Awolowo University Teaching Hospitals Complex in Ile-Ife, Nigeria.
Methods: We analyzed data from 545 patients with GI cancer in the African Research Group for Oncology (ARGO) database.
Background: West Africa has among the highest rates of hepato-pancreato-biliary (HPB) malignancies in the world. Although surgery is critical for treatment, the availability of HPB surgery in Africa is unknown. This cross-sectional study investigated the current HPB surgical capacity of West African hospitals.
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- * A training program was tailored to healthcare providers in Nigeria, focusing on empathic communication skills to help lessen stigma associated with lung cancer.
- * The study showed that after the training, healthcare providers reported significant increases in their self-efficacy and empathy levels towards lung cancer patients, as well as a more positive attitude towards lung cancer care.
Article Synopsis
- The study aimed to identify issues related to the safe handling and disposal of chemotherapy agents in low and middle-income countries, focusing on Nigeria.
- Two surveys were conducted: one assessing the needs of health professionals in 2019 and another evaluating a chemotherapy facility's compliance with safety standards in 2021.
- Results revealed significant gaps in training and satisfaction with current practices, indicating a pressing need for improved resources and strategies to ensure safe chemotherapy administration.
Globally, cancer is the second leading cause of death, and low- and middle-income countries bear most of the disease burden. While cancer is increasingly recognized as a major global health issue, more work remains. Understanding the status of global cancer care will shape the next steps in ensuring equitable global access to cancer care.
View Article and Find Full Text PDFObjective: Cancer is a leading global health challenge with increasing morbidity and mortality. In Nigeria, cancer leads to over 100,000 new cases and 70,000 deaths annually. In resource-constrained countries such as Nigeria, registered nurses (RNs) that provide oncology care lack specialty education in oncology nursing care.
View Article and Find Full Text PDFImmediate lymph node extraction improves retrieval rate following axillary lymph node dissection: an effective approach to improving guideline-concordant breast cancer care in Nigeria.
Ecancermedicalscience
October 2023
Background: Axillary lymph node staging is essential for making therapeutic decisions and for prognostication. A minimum of ten lymph nodes is recommended for accurate staging. This study describes the process and outcomes of an audit cycle that resulted in a novel intervention instituted to improve concordance with guidelines.
View Article and Find Full Text PDFInsulinomas are functioning pancreatic neuroendocrine tumors (NETs). They secrete insulin, and hence, present with hypoglycemia. We report a case of insulinoma in a 16-year-old girl presenting as seizures.
View Article and Find Full Text PDFPurpose: Mammography, breast ultrasound (US), and US-guided breast biopsy are essential services for breast cancer early detection and diagnosis. This study undertook a comprehensive evaluation to determine population-level access to these services for breast cancer early detection and diagnosis in Nigeria using a previously validated geographic information system (GIS) model.
Methods: A comprehensive list of public and private facilities offering mammography, breast US, and US-guided breast biopsy was compiled using publicly available facility data and a survey administered nationally to Nigerian radiologists.
Purpose: Hepatocellular carcinoma (HCC), the fourth most common cancer in Africa, has a dismal overall survival of only 3 months like in sub-Saharan Africa. This is affected by the low gross domestic product and human development index, absence of coherent guidelines, and other factors.
Methods: An open forum for HCC-experienced health care workers from Africa and the rest of the world was held in October 2021.
The African Research Group for Oncology (ARGO) was formed in 2013 to undertake methodologically rigorous cancer research in Nigeria, and to strengthen cancer research capacity in the country through training and mentorship of physicians, scientists, and other healthcare workers. Here, we describe how ARGO's work in colorectal cancer (CRC) has evolved over the past decade. This includes the consortium's scientific contributions to the understanding of CRC in Nigeria and globally and its research capacity-building program.
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- Breast cancer survivors in Nigeria represent a growing population with specific characteristics and needs, highlighting the importance of improving support and treatment outcomes.
- Data from a breast cancer database showed that 45.9% of patients were survivors after five years, with survival linked to factors like age, stage at diagnosis, and treatment approaches.
- Qualitative interviews revealed key themes around their experiences, emphasizing the role of strong family support and spirituality as vital coping mechanisms, while also pointing to unmet psychosocial and physical needs.
Improving access to breast cancer screening and treatment in Nigeria: The triple mobile assessment and patient navigation model (NCT05321823): A study protocol.
PLoS One
June 2023
Background: In Nigeria, breast cancer incidence is rising, late presentation is common, and outcomes are poor. Patient-related factors such as lack of awareness and misperceptions in addition to health system deficiencies such as lack of a clearly defined framework for breast cancer screening and referral are some of the major drivers of this poor outlook. Guidelines for breast cancer screening in high-income countries have limited applicability in low-middle-income countries, hence the need for innovative, resource-compatible strategies to combat the negative trend.
View Article and Find Full Text PDFPurpose: Cancer burden is rising rapidly in Nigeria, the most populous country in sub-Saharan Africa; this trend may in part be attributable to diet. We developed and validated a semi-quantitative food frequency questionnaire (FFQ) to assess regional diet in Nigeria.
Methods: We recruited 68 adult participants from rural and urban settings in South West Nigeria.
Background: Breast cancer in the elderly population has not been evaluated in the Nigerian context. With the rising incidence of breast cancer and the changing demographics, it is likely that an increasing number of elderly patients will be managed in the coming years in Nigeria. This review describes the clinicopathological profile of elderly patients with breast cancer in a Nigerian database.
View Article and Find Full Text PDFIntroduction: Research is a critical pillar in national cancer control planning. However, there is a dearth of evidence for countries to implement affordable strategies. The WHO and various Commissions have recommended developing stakeholder-based needs assessments based on objective data to generate evidence to inform national and regional prioritisation of cancer research needs and goals.
View Article and Find Full Text PDFBackground: Cancers are a disease of growing public health importance in Africa, but cancer research capacity in the region is underdeveloped. The quest to foster and promote locally conceptualized and conducted oncology research in Africa have informed the African Research Group for Oncology's (ARGO) research capacity-building efforts in Nigeria.
Aim: To evaluate the effectiveness of oncology research capacity-building initiatives among Nigerian senior trainees and junior faculty physicians.