A Comparison Study of Person Identification Using IR Array Sensors and LiDAR.

Person identification is a critical task in applications such as security and surveillance, requiring reliable systems that perform robustly under diverse conditions. This study evaluates the Vision Transformer (ViT) and ResNet34 models across three modalities-RGB, thermal, and depth-using datasets collected with infrared array sensors and LiDAR sensors in controlled scenarios and varying resolutions (16 × 12 to 640 × 480) to explore their effectiveness in person identification. Preprocessing techniques, including YOLO-based cropping, were employed to improve subject isolation.

Novel Drug Delivery Particles Can Provide Dual Effects on Cancer "Theranostics" in Boron Neutron Capture Therapy.

Boron (B) neutron capture therapy (BNCT) is a novel non-invasive targeted cancer therapy based on the nuclear capture reaction B (n, alpha) Li that enables the death of cancer cells without damaging neighboring normal cells. However, the development of clinically approved boron drugs remains challenging. We have previously reported on self-forming nanoparticles for drug delivery consisting of a biodegradable polymer, namely, "AB-type" Lactosome nanoparticles (AB-Lac particles)- highly loaded with hydrophobic B compounds, namely -Carborane (Carb) or 1,2-dihexyl--Carborane (diC6-Carb), and the latter (diC6-Carb) especially showed the "molecular glue" effect.

Long-term changes in carotid intima-media thickness according to baseline blood pressure level: J-STARS Echo study.

Background And Aims: We aimed to investigate long-term changes in carotid intima-media thickness (IMT) based on baseline blood pressure (BP) levels in non-cardioembolic stroke patients.

Methods: Patients aged 45-80 years with dyslipidemia who were not on statins before enrollment and had experienced a non-cardioembolic stroke were assigned to either the pravastatin group or the control group in a randomized trial. Patients were classified into three groups according to BP levels: normal BP (N-group: systolic BP [sBP] <140 mmHg and diastolic BP [dBP] <90 mmHg), highly elevated BP (G2 group: sBP ≥160 mmHg or dBP ≥100 mmHg), and mildly elevated BP (G1 group: the remaining patients).

Surgical outcome and contributing presurgical evaluations in children with magnetic resonance imaging-negative epilepsy and periodic seizure cycles.

Background: The identification of surgical candidates is a critical issue in patients with magnetic resonance imaging (MRI)-negative drug-resistant focal epilepsy and latent accompanying resectable lesions, such as focal cortical dysplasia (FCD). Recently, periodic seizure cycles have been associated with FCD in both patients with MRI-positive and MRI-negative epilepsy. We investigated the presurgical evaluation and postsurgical outcome of patients with MRI-negative epilepsy with FCD and a history of periodic seizure cycles.

Distribution and Incorporation of Extracellular Vesicles into Chondrocytes and Synoviocytes.

Osteoarthritis (OA) is a chronic disease affecting over 500 million people worldwide. As the population ages and obesity rates rise, the societal burden of OA is increasing. Pro-inflammatory cytokines, particularly interleukin-1β, are implicated in the pathogenesis of OA.

Non-Contact Cross-Person Activity Recognition by Deep Metric Ensemble Learning.

In elderly monitoring or indoor intrusion detection, the recognition of human activity is a key task. Owing to several strengths of Wi-Fi-based devices, including their non-contact and privacy protection, these devices have been widely applied in the area of smart homes. By the deep learning technique, numerous Wi-Fi-based activity recognition methods can realize satisfied recognitions, however, these methods may fail to recognize the activities of an unknown person without the learning process.

Heart Rate Estimation Considering Reconstructed Signal Features Based on Variational Mode Decomposition via Multiple-Input Multiple-Output Frequency Modulated Continuous Wave Radar.

Accurate heart rate estimation using Doppler radar and Frequency Modulated Continuous Wave (FMCW) radar is highly valued for privacy protection and the ability to measure through clothing. Conventional methods struggle to isolate the heartbeat from respiration and body motion. This paper introduces a novel heart rate estimation method using Variational Mode Decomposition (VMD) via Multiple-Input Multiple-Output (MIMO) FMCW radar.

Optimized medium conditions maximize colony regeneration from a single cell of Botryococcus braunii NIES836.

Botryococcus braunii is a colonial alga recognized for its slow growth but high hydrocarbon accumulation. Although using genetic engineering to increase the growth rate and hydrocarbon yield of B. braunii is desirable, the presence of an extracellular matrix (ECM) significantly hinders the emergence of a homogeneous colony from a single DNA-transformed cell.

Configuration of two cysteine residues in a ring within a stapled Bim peptide affects the secondary structure and apoptotic activity.

Many reports have shown that stabilization of secondary structure by stapling functional peptides enhances the intracellular bioactivity. However, no report has discussed the correlation between stabilization and biological activity based on the configuration of amino acid residues used as anchors for stapling. To clarify this, we investigated the helix content and apoptotic efficiency of an apoptosis-inducing peptide, Bim, and four stapled Bim peptides containing stapling-related Cys residues introduced with different configurations within the sequence.

Development of an HPLC method using relative molar sensitivity for the measurement of blood concentrations of nine pharmaceutical compounds.

We developed a reliable high-performance liquid chromatographic analysis method using a relative molar sensitivity (RMS) technique that does not require an authentic, identical reference analyte material to quantify blood serum carbamazepine, phenytoin, voriconazole, lamotrigine, meropenem, mycophenolic acid, linezolid, vancomycin, and caffeine levels for routine blood concentration measurements. Carbamazepine and caffeine were also used as non-analyte reference materials to calculate the RMS of each analyte. The RMS was calculated from the ratio of the slope of the calibration equation (analyte/non-analyte reference material), then used to quantify analytes in control serum samples spiked with carbamazepine, phenytoin, voriconazole, meropenem, mycophenolic acid, linezolid or vancomycin.

In Vitro Study of Tumor-Homing Peptide-Modified Magnetic Nanoparticles for Magnetic Hyperthermia.

Cancer cells have higher heat sensitivity compared to normal cells; therefore, hyperthermia is a promising approach for cancer therapy because of its ability to selectively kill cancer cells by heating them. However, the specific and rapid heating of tumor tissues remains challenging. This study investigated the potential of magnetic nanoparticles (MNPs) modified with tumor-homing peptides (THPs), specifically PL1 and PL3, for tumor-specific magnetic hyperthermia therapy.

Activity Detection in Indoor Environments Using Multiple 2D Lidars.

In health monitoring systems for the elderly, a crucial aspect is unobtrusively and continuously monitoring their activities to detect potentially hazardous incidents such as sudden falls as soon as they occur. However, the effectiveness of current non-contact sensor-based activity detection systems is limited by obstacles present in the environment. To overcome this limitation, a straightforward yet highly efficient approach involves utilizing multiple sensors that collaborate seamlessly.

A Robust Approach Assisted by Signal Quality Assessment for Fetal Heart Rate Estimation from Doppler Ultrasound Signal.

Fetal heart rate (FHR) monitoring, typically using Doppler ultrasound (DUS) signals, is an important technique for assessing fetal health. In this work, we develop a robust DUS-based FHR estimation approach complemented by DUS signal quality assessment (SQA) based on unsupervised representation learning in response to the drawbacks of previous DUS-based FHR estimation and DUS SQA methods. We improve the existing FHR estimation algorithm based on the autocorrelation function (ACF), which is the most widely used method for estimating FHR from DUS signals.

Phylogenetic, population structure, and population demographic analyses reveal that Vicia sepium in Japan is native and not introduced.

Vicia sepium (bush vetch) is a perennial legume widely distributed throughout the Eurasian continent. However, its distribution in Japan is limited to Mt. Ibuki and small parts of central and southern Hokkaido.

A simple method for the preparation of single cells and regeneration of colonies of Botryococcus braunii NIES836.

Botryococcus braunii, a colonial alga, is known for notably slow growth; however, the growth rate and hydrocarbon productivity are expected to be improved using genetic modification techniques. Nevertheless, B. braunii has a hydrocarbon-rich extracellular matrix (ECM), and the ECM is a major barrier to DNA transformation.

Resource Allocation for Secure MIMO-SWIPT Systems in the Presence of Multi-Antenna Eavesdropper in Vehicular Networks.

In this paper, we optimize the secrecy capacity of the legitimate user under resource allocation and security constraints for a multi-antenna environment for the simultaneous transmission of wireless information and power in a dynamic downlink scenario. We study the relationship between secrecy capacity and harvested energy in a power-splitting configuration for a nonlinear energy-harvesting model under co-located conditions. The capacity maximization problem is formulated for the vehicle-to-vehicle communication scenario.

Anisotropic Topological Anderson Transitions in Chiral Symmetry Classes.

We study quantum phase transitions of three-dimensional disordered systems in the chiral classes (AIII and BDI) with and without weak topological indices. We show that the systems with a nontrivial weak topological index universally exhibit an emergent thermodynamic phase where wave functions are delocalized along one spatial direction but exponentially localized in the other two spatial directions, which we call the quasilocalized phase. Our extensive numerical study clarifies that the critical exponent of the Anderson transition between the metallic and quasilocalized phases, as well as that between the quasilocalized and localized phases, are different from that with no weak topological index, signaling the new universality classes induced by topology.

Photo-dependent cytosolic delivery of shRNA into a single blastomere in a mouse embryo.

Single-cell-specific delivery of small RNAs, such as short hairpin RNA (shRNA) and small noncoding RNAs, allows us to elucidate the roles of specific upregulation of RNA expression and RNAi-mediated gene suppression in early embryo development. The photoinduced cytosolic dispersion of RNA (PCDR) method that we previously reported can introduce small RNAs into the cytosol of photoirradiated cells and enable RNA delivery into a single-cell in a spatiotemporally specific manner. However, the PCDR method has only been applied to planer cultured cells and not to embryos.

Detecting Dementia from Face-Related Features with Automated Computational Methods.

Alzheimer's disease (AD) is a type of dementia that is more likely to occur as people age. It currently has no known cure. As the world's population is aging quickly, early screening for AD has become increasingly important.

A quantitative description of the compatibility of technetium-selective chromatographic technetium-99m separation with low specific activity molybdenum-99.

Technetium-99m generators employing a technetium-selective stationary phase are a chromatographic instrument developed for use with Mo having low specific activity (LSA); particularly, Mo produced by electron accelerators. This paper presents a mathematical description of technetium-selective chromatographic (TSC) Tc separation and analyzes its compatibility with LSA Mo. We developed a theoretical formula for TSC Tc separation by discretizing its pertechnetate selectivity, and validated it using an electron linear accelerator and activated carbon-based TSC (AC-TSC) Tc generators.

Associations between Drug Use and Sexual Risk Behaviours among Men Who Have Sex with Men in Japan: Results from the Cross-Sectional LASH Study.

This study assessed drug use patterns among men who have sex with men (MSM) in Japan, and evaluated their potential associations with sexual risk behaviours. Between September and October 2016, study subjects were recruited through a cross-sectional survey (LASH: Love Life and Sexual Health) using a geosocial networking application for MSM. Of the participants, 25.

Molecular Identification of UDP-Sugar-Dependent Glycosyltransferase and Acyltransferase Involved in the Phenylethanoid Glycoside Biosynthesis Induced by Methyl Jasmonate in Sesamum indicum L.

Sesame (Sesamum indicum L.) plants contain large amounts of acteoside, a typical phenylethanoid glycoside (PhG) that exhibits various pharmacological activities. Although there is increasing interest in the biosynthesis of PhGs for improved production, the pathway remains to be clarified.

FRET probe for detecting two mutations in one mRNA.

Technologies for visualizing and tracking RNA are essential in molecular biology, including in disease-related fields. In this study, we propose a novel probe set (DAt-probe and T-probe) that simultaneously detects two mutations in the same RNA using fluorescence resonance energy transfer (FRET). The DAt-probe carrying the fluorophore Atto488 and the quencher Dabcyl were used to detect a cancer mutation (exon19del), and the T-probe carrying the fluorophore Tamra was used to detect drug resistance mutations (T790M) in () mRNA.

Adjusting Heterodimeric Coiled-Coils (K/E Zipper) to Connect Autophagy-Inducing Peptide with Cell-Penetrating Peptide.

A connection of a functional peptide with a cell-penetrating peptide (CPP) used a heterodimeric coiled-coil as a molecular zipper can improve the intracellular delivery and activity of the functional peptide. However, the chain length of the coiled coil required for functioning as the molecular zipper is unknown at present. To solve the problem, we prepared an autophagy-inducing peptide (AIP) that conjugates with the CPP via heterodimeric coiled-coils consisting of 1 to 4 repeating units (K/E zipper; AIP-Kn and En-CPP), and we investigated the optimum length of the K/E zipper for effective intracellular delivery and autophagy induction.

A 2D-Lidar-Equipped Unmanned Robot-Based Approach for Indoor Human Activity Detection.

Monitoring the activities of elderly people living alone is of great importance since it allows for the detection of when hazardous events such as falling occur. In this context, the use of 2D light detection and ranging (LIDAR) has been explored, among others, as a way to identify such events. Typically, a 2D LIDAR is placed near the ground and collects measurements continuously, and a computational device classifies these measurements.