Meconium periorchitis: case report and literature review.

Meconium periorchitis (MPO) is an uncommon entity associated with healed meconium peritonitis. The typical presentation is soft hydrocele at birth which becomes harder in weeks as the meconium calcifies. It mimics a scrotal mass, and, without knowledge of this rare disease, this may lead to unnecessary surgery.

Lung hypoplasia and severe pulmonary hypertension in an infant with double heterozygosity for spondyloepiphyseal dysplasia congenita and achondroplasia.

A rare instance of double heterozygosity for spondyloepiphyseal dysplasia congenita and achondroplasia is presented. Despite midface hypoplasia, thorax deformity and lung hypoplasia, the child survived the neonatal period. Severe pulmonary hypertension, already present at birth, led to right heart failure and death at the age of 1 year.

A new case of malignant mesothelioma of the tunica vaginalis testis. Immunohistochemistry in comparison with an adenomatoid tumor of the testis.

Malignant mesothelioma of the tunica vaginalis testis is an extremely rare tumor with 41 previously reported cases. The histological and immunohistological features of a new case in an 80-year-old patient are described and compared with an adenomatoid tumor of the tunica vaginalis testis, which is considered to be the benign variant of malignant mesothelioma. Both tumors revealed strong cytoplasmic staining for a panepithelial antibody (Lu-5) and membranous staining for BMA-120 (a mesothelial/endothelial cell marker) but yielded negative staining results with the endothelial cell markers QBend-10 (CD 34), Factor VIII-related antigen (vWF) and UEA-1.

[Leiomyosarcoma of the breast 16 years following successful treatment of a rhabdomyosarcoma of the orbit in childhood].

A case of a mammary leiomyosarcoma in a 23-year-old woman is presented. The tumor appeared 16 years after successful treatment of an embryonal rhabdomyosarcoma of the orbit. Rhabdomyosarcomas are the most frequent soft tissue tumors of childhood, the orbit and the paratesticular region being the most common primary site for this tumor.

[Plasma cell granuloma of the lung].

Isolated primary tumors of the lung are rarely seen in childhood and are benign in one third of the patients. Plasma cell granulomas represent the most common benign tumor of the lung in this age group. Histologically, the tumor is characterized by the various components of a chronic inflammation or granulation tissue.

[Cervical thymic cyst in childhood].

In three children (2, 4 and 10 years of age) a cervical thymic cyst was removed. We found multilocular cysts with xanthochromic luminal fluid covered with a fibrous capsule. Histological features are lymphatic follicles, partly atrophic, as well as regular thymic tissue with cortex, marrow and Hassall's corpuscles.

Mesenterial histiocytic necrotizing lymphadenitis. Case report.

A 14-year-old girl was hospitalized with fever, jaundice, vomiting and right sided abdominal pain. A laparotomy was performed because of muscular defence and ascites. There was a mass of enlarged red and blue colored lymph nodes in the mesentery of the lower ileum loop.

Zuelzer-Wilson's syndrome and absence of the enteric nervous system. Two rare forms of anomalies of the enteric nervous system with identical clinical symptoms.

47 children have been treated in Basel for aganglionosis (Hirschsprung's disease) during the last 25 years. Six children presented severe vomiting and an ileus as leading symptoms instead of chronic constipation, the classical leading symptom of Hirschsprung's disease. Clinical, radiological and intraoperative findings were virtually identical in these 6 patients.

Absence of the enteric nervous system in the newborn: presentation of three patients and review of the literature.

Three patients suffering from an absence of the enteric nervous system are reported. Two sisters presented with severe vomiting shortly after birth and dilatation of the intestine proximal to a stenosis. There was an absence of the enteric nervous system throughout the entire length of the intestine distal to the duodenum.

[Ganglion in the discus triangularis. First description].

A fifty-four year old patient had persisting pain in the wrist following a distal radius fracture two years previously. A perforation of the discus triangularis was confirmed by arthrography, and the disc removed. Gelatinous fluid was found in the joint at operation.

[How reliable is cancer diagnosis with needle biopsy of the prostate?].

Aim of the study was to investigate the reproducibility and the reliability of the morphological diagnosis, of different morphological parameters and representativity of needle biopsy material compared with transurethral resection material. 416 needle biopsies of carcinomas of the prostate were studied by 5 pathologists. 130 biopsies were evaluated twice by the same investigators and 325 at least by one other investigator.

[Prognostic significance of clinical and morphological parameters in prostate cancer].

In 269 patients with carcinoma of the prostate, a retrospective statistical evaluation was done to correlate prognosis with different clinical and morphological criteria. All prostate biopsies were reviewed, the clinical staging redone and compared to survival of the patients. The most reliable criteria for prognostic prediction are clinical staging (rectal palpation, radiological examination and prostatic acid phosphatase).

[Diagnostic accuracy of prostate needle biopsies in cancer of the prostate].

The carcinoma of the prostate can be diagnosed with high certainty in needle biopsy. Among 450 cases only one false diagnosis was found. Under routine diagnostic conditions, semiquantitative evaluation showed that 50% of the investigated morphological parameters in carcinomas of the prostate can be reproduced by one and the same or different investigators with a sufficiently high degree of certainty.