[TOTAL RECONSTRUCTION OF CONGENITAL MICROTIA - OUR EXPERIENCE WITH 150 PATIENTS].

Aims: In this article, we would like to present our experience in total ear reconstruction for microtic ear patients.

Background: Partial and total ear reconstruction is one of the most challenging reconstruction procedures in plastic surgery. Ear reconstruction is performed in cases of congenital malformations such as anotia or microtia.

A randomized, controlled, clinical pilot study assessing the analgesic effect of morphine applied topically onto split-thickness skin wounds.

Objectives: To assess the effect of an opioid administered topically onto a standardized skin wound in patients without significant comorbidity. Findings to date are contradictory, often obtained from multimorbid patients with wounds lacking uniformity.

Methods: Forty-four patients undergoing surgery for skin grafting were randomly assigned to receive morphine (0.

The chemokine stromal cell-derived factor-1α promotes endothelial progenitor cell-mediated neovascularization of human transplanted fat tissue in diabetic immunocompromised mice.

Background: Stromal cell-derived factor-1α is a chemokine and mediates endothelial progenitor cell-induced neovascularization. Because vascularization of a graft is crucial for its survival, the authors investigated whether stromal cell-derived factor-1α could improve fat graft survival by inducing endothelial progenitor cell-mediated neovascularization and preventing its resorption.

Methods: The authors injected 1 ml of human fat tissue into the scalps of 30 diabetic and 10 nondiabetic immunocompromised mice.

Treating fat grafts with human endothelial progenitor cells promotes their vascularization and improves their survival in diabetes mellitus.

Background: Bone marrow-derived endothelial progenitor cells are required for vascularization of a fat graft to form a functional microvasculature within the graft and to facilitate its integration into the surrounding tissues. Organ transplantation carries a high risk of graft loss and rejection in patients with diabetes mellitus because endothelial progenitor cell function is impaired. The authors investigated the influence of endothelial progenitor cell treatment on the phenotype and survival of human fat grafts in immunocompromised mice with experimentally induced diabetes mellitus.