Publications by authors named "Oguz Bilal Karakus"

Article Synopsis
  • A study from Istanbul compared psychiatric admission and diagnosis rates in children and adolescents during the first three months of the COVID-19 pandemic with the same periods in the previous year.
  • The results showed significant increases in diagnoses of autism spectrum disorder (ASD), obsessive-compulsive disorder (OCD), intellectual disability (ID), attention-deficit hyperactivity disorder (ADHD), and depression during the pandemic compared to previous periods.
  • The findings indicate a notable rise in pediatric neurodevelopmental disorders, particularly ASD, due to the initial phase of the pandemic.
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Article Synopsis
  • Mental disorders impact about 15%-20% of children, yet many do not receive adequate mental health care, making psychiatric emergency services crucial for treatment.
  • The study analyzed data from 785 patients aged 0-18 who visited a psychiatric emergency department over a year, categorizing them as either single or repeated applicants based on their number of visits.
  • Findings revealed that recurrent applicants exhibited higher instances of non-suicidal self-injury, psychotic disorders, and major depression, suggesting specific risk factors that contribute to multiple emergency admissions and indicating a need for tailored community resources.
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Anxiety comorbidity in bipolar disorder (BD) is important and thus significantly affects the course of BD and its outcomes. The treatment of generalized anxiety disorder comorbid with BD involves certain challenges, as antidepressant medications, which are standard in the treatment of anxiety disorder, have the risk of shifting to manic episodes and rapid cycling. In this case report, the response to agomelatine treatment in generalized anxiety disorder comorbid with bipolar 1 disorder was evaluated.

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Objectives: Lifetime co-occurring substance use disorders are common at the time of presentation for the treatment of primary psychosis. Our aim was to investigate the clinical characteristics of adolescents with early-onset schizophrenia/schizoaffective disorder (EOS), categorized as either with (EOS + SUD) or without SUD (non-SUD/EOS), in a multi-center sample.

Methods: Between 2016 and 2022, 255 patients were evaluated across three tertiary-care inpatient units.

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Previous studies demonstrated neurocognitive impairments in early-onset schizophrenia (EOS) and other psychotic spectrum disorders (PSD). This study aimed to compare remitted and symptomatic cases in terms of neurocognition and theory of mind (ToM). 50 healthy controls (HC) and 106 patients diagnosed schizophrenia in remission (EOS-R, n = 38), symptomatic schizophrenia (EOS-S, n = 34), and other PSD (n = 34) were included in our study.

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Persistent negative symptoms (PNS) contribute to impairment in psychosis. The characteristics of PNS seen in youth remained under-investigated. We aimed to demonstrate clinical, treatment-related, and psychosocial characteristics of PNS in early-onset schizophrenia-spectrum disorders (EOSD).

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