Odontogenic Tumours: A Clinicopathologic Appraisal of Cases seen in a Nigerian Tertiary Hospital using 2017 WHO Classification.

Background: Odontogenic tumours (OT) are a group of diverse lesions seen in the maxillofacial region. They are categorized according to their tissues of origin as; epithelial, mesenchymal or mixed tumours.

Objectives: The aim of this study is to present the proportion of odontogenic tumours seen in Lagos University Teaching Hospital using the 2017 WHO classification.

Transfection Efficacy and Cellular Uptake of Lipid-Modified Polyethyleneimine Derivatives for Anionic Nanoparticles as Gene Delivery Vectors.

Cationic polyethylenimine (PEI)-based nonviral gene carriers have been desirable to overcome the limitations of viral vectors in gene therapy. A range of PEI derivatives were designed, synthesized, and evaluated for nonviral delivery applications of plasmid DNA (pDNA). Linolenic acid, lauric acid, and oleic acid were covalently conjugated with low-molecular-weight PEI ( ∼ 1200 Da) via two different linkers, gallic acid (GA) and -hydroxybenzoic acid (PHPA), that allows a differential loading of lipids per modified amine (3 vs 1, respectively).

An evidence-based surgical algorithm for management of odontogenic keratocyst.

The effective management of odontogenic keratocyst (OKC) remains a subject of interest and confusion in the oral and maxillofacial surgery literature. Currently, there is a lack of consensus regarding the most appropriate treatment for patients with OKC. Of the various treatment options available, no modality to date has been shown to demonstrate a zero or near-zero recurrence rates except wide resection with clear margins.

Mercury hygiene and biomedical waste management practices among dental health-care personnel in public hospitals in Lagos State, Nigeria.

Background: Indiscriminate disposal of hospital wastes including mercury/amalgam wastes pose a serious threat to life and environment. There is a growing concern about biomedical waste (BMW) management among health care workers, however there are limited reports on BMW management by dental personnel in developing countries.

Objectives: This study investigated the level of knowledge of BMW, observance of proper mercury hygiene and BMW management practice among public dental personnel in Lagos State, Nigeria.

Plunging ranula: surgical management of case series and the literature review.

Plunging ranulas are rare; report of this condition is particularly limited in our environment. We present case series in children; with all cases having both oral and cervical components. It is important to note this type of presentation of plunging ranula and their appropriate management.

PATTERN OF ASSAULT-RELATED MAXILLOFACIAL INJURIES TREATED AT THE GENERAL HOSPITAL, LAGOS, NIGERIA.

Background: The human face often constitutes the first point of contact in various human interactions and it is frequently the preferred target for blows in assault cases.

Aim: To analyze the pattern of assault-related maxillofacial injuries treated at the General Hospital, Lagos over a period of one year.

Methodology: This is one year prospective study of assault-related maxillofacial injuries treated at the Department of Oral-Maxillofacial Surgery, Dental Centre, General Hospital, Lagos, Nigeria.

Pattern of distribution of odontogenic tumours in sub-Saharan Africa.

Objective: To analyse documented reports on odontogenic tumours (OTs) in sub-Saharan Black Africa and to create awareness of the need for more reports on this topic.

Methods: There were 2,186 African cases of OTs presented at the International Association of Oral and Maxillofacial Pathologists (IAOP) Congress (Cape Town, South Africa) in 1998 that were added to 2,198 cases derived from reports published in the scientific literature from 1998 to date. The analysis undertaken included frequency distribution of available data on OTs that was listed in the 2005 World Health Organization (WHO) classification.

Ameloblastoma: current etiopathological concepts and management.

Ameloblastoma is a benign odontogenic tumor of epithelial origin. It is locally aggressive with unlimited growth capacity and has a high potential for malignant transformation as well as metastasis. Ameloblastoma has no established preventive measures although majority of patients are between ages 30 and 60 years.

TEMPOROMANDIBULAR PAIN DYSFUNCTION SYNDROME IN PATIENTS ATTENDING LAGOS UNIVERSITY TEACHING HOSPITAL, LAGOS, NIGERIA.

Background: Temporomandibular joint pain dysfunction syndrome (TMJPDS) is the most common temporomandibular disorder. This condition presents with symptoms of pain, restricted jaw movement and joint noise. Other symptoms include otalgia, headache, neck pain and trismus.

Analysis of Elastic Tissue in Histological Variants of Pleomorphic Salivary Adenoma seen at the Lagos University Teaching Hospital over a period of 35 Years.

Background: Pleomorphic salivary adenoma (PSA), is known for its morphologic diversity. While reports of elastic tissue in PSA have been documented, the distribution of this tissue in histological variants of the tumour has not been documented. Perhaps such features may influence biological behaviour of these variants.

Clinicohistopathological analysis of 5 Nigerian cases of malignant fibrous histiocytoma of the jaws.

Background: Malignant fibrous histiocytoma (MFH), is a soft tissue sarcoma that occurs predominantly in the soft tissue of the extremities. It rarely occurs in facial bones. Few cases in the jaws have been reported.