Publications by authors named "Oghenetejiri V Smith"

Article Synopsis
  • Facial expressions play a crucial role in social interactions and can influence behavior by conveying emotions, but how this ability varies between genders and is affected by anxiety is not well understood.
  • A study using fMRI involved 191 youth (ages 6 to 15) to assess how sex and anxiety impact brain responses to emotional faces, focusing on angry, happy, and neutral expressions.
  • Results showed that anxiety levels interacted with sex, where anxious girls exhibited weaker brain activation in response to happy faces, whereas anxious boys showed stronger activation, highlighting the complexity of emotional processing influenced by gender and anxiety.
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The refinement of brain morphology extends across childhood, and exposure to environmental toxins during this period may alter typical trends. Radon is a highly common radiologic toxin with a well-established role in cancer among adults. However, effects on developmental populations are understudied in comparison.

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Introduction: It is well-established that chronic exposure to environmental toxins can have adverse effects on neuropsychological health, particularly in developing youths. However, home radon, a ubiquitous radiotoxin, has been seldom studied in this context. In the present study, we investigated the degree to which chronic everyday home radon exposure was associated with alterations in transdiagnostic mental health outcomes.

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Children are particularly vulnerable to the deleterious impacts of toxic environmental exposures, though the effects of some rather ubiquitous toxins have yet to be characterized in youths. One such toxin, radon gas, is known to accumulate to hazardous levels in homes, and has been linked with the incidence of lung cancer in aging adults. However, the degree to which chronic home radon exposure may impact risk for health problems earlier in life is unknown.

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Neuroblastoma (NB) is an enigmatic and deadliest pediatric cancer to treat. The major obstacles to the effective immunotherapy treatments in NB are defective immune cells and the immune evasion tactics deployed by the tumor cells and the stromal microenvironment. Nervous system development during embryonic and pediatric stages is critically mediated by non-coding RNAs such as micro RNAs (miR).

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