Publications by authors named "Ogale Y"

Background: The 2022 mpox outbreak in the United States disproportionately affected gay, bisexual, and other men who have sex with men (GBMSM). Uptake of mpox testing may be related to symptomology, sociodemographic characteristics, and behavioral characteristics.

Objective: This study aimed to describe suspected mpox symptoms and testing uptake among a sample of GBMSM recruited via the internet in the United States in August 2022.

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Article Synopsis
  • In May 2023, an increase in mpox cases was observed in Chicago, primarily among fully vaccinated individuals, prompting an investigation into the outbreak's characteristics and causes.
  • Researchers assessed demographic and health data from patients, analyzed viral genomes, and evaluated the humoral antibody responses to understand vaccine effectiveness and potential compromises.
  • Of the 49 identified cases, 57% were fully vaccinated, with findings suggesting that increased exposure through higher median numbers of sexual partners was a key factor in the outbreak, despite overall vaccine effectiveness.
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From 2020 to 2021, Marion County, Indiana, USA, saw an increase in early syphilis diagnoses, primarily among gay, bisexual, and other men who have sex with men (GBMSM). This rapid ethnographic assessment combines survey data from GBMSM with data from key informant interviews with multiple groups of stakeholders, including GBMSM, to describe how COVID-19 impacted sexual behaviors, sexual decision-making, and access to sexually transmitted disease (STD) services among GBMSM in Marion County, Indiana. A total of 62 virtual, semi-structured qualitative interviews with 72 key respondents including health department staff, medical providers, community-based organization staff, and GBMSM were conducted from October 14 to November 22, 2021.

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Introduction: Self-collected samples (SCS) for sexually transmitted infection (STI) testing have been shown to be feasible and acceptable in high-resource settings. However, few studies have assessed the acceptability of SCS for STI testing in a general population in low-resource settings. This study explored the acceptability of SCS among adults in south-central Uganda.

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Understanding treatment-seeking behavior is critical to the treatment and control of sexually transmitted infections (STIs), yet current data on STI treatment seeking in low-resource settings is rare. This population-based study aimed to describe STI treatment-seeking behavior and identify factors associated with seeking treatment at a clinic among adults with STI-related symptoms in rural Uganda. The STI prevalence study (STIPS) conducted a survey and STI testing among all consenting adults aged 18-49 in two communities in rural south-central Uganda.

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Article Synopsis
  • Chancroid, a sexually transmitted infection, has been reportable in the U.S. since 1944, but since 2011, fewer than 20 cases have been reported annually, raising questions about the effectiveness of national surveillance.
  • A recent study assessed the quality and usefulness of the National Notifiable Diseases Surveillance System for chancroid, finding low data quality and sensitivity due to limited diagnostic testing and clinician awareness.
  • The findings suggest that the current surveillance system is inadequate for monitoring trends in chancroid cases, prompting a reevaluation of its status as a notifiable condition and the need for alternative monitoring strategies.
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The first three SARS-CoV-2 phylogenetic lineages classified as variants of concern (VOCs) in the United States (U.S.) from December 15, 2020 to February 28, 2021, Alpha (B.

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Article Synopsis
  • - Mpox vaccination is advised for individuals who have been exposed to or are at risk for mpox, with only 25% of a sample of men who have sex with men (MSM) reporting vaccination.
  • - Vaccination rates are higher among younger MSM, those worried about mpox, and those engaging in sexual risk behaviors.
  • - To prevent mpox spread, it is important to integrate mpox vaccination into regular sexual health services and to boost the uptake of the complete 2-dose series.
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Article Synopsis
  • - The study examined the prevalence of mpox virus in blood, throat, and rectal samples from people without visible rashes who were seeking the JYNNEOS vaccine.
  • - Findings suggest that testing individuals without skin lesions for mpox using throat, rectal, or blood samples may not be very effective.
  • - This raises questions about the practicality of risk-based screening for mpox in those who do not show typical symptoms.
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Introduction: Self-collected samples (SCS) for sexually transmitted infection (STI) testing have been shown to be feasible and acceptable in high-resource settings. However, few studies have assessed the acceptability of SCS for STI testing in a general population in low-resource settings. This study explored the acceptability of SCS among adults in south-central Uganda.

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On May 17, 2022, the Massachusetts Department of Public Health (MDPH) Laboratory Response Network (LRN) laboratory confirmed the presence of orthopoxvirus DNA via real-time polymerase chain reaction (PCR) from lesion swabs obtained from a Massachusetts resident. Orthopoxviruses include Monkeypox virus, the causative agent of monkeypox. Subsequent real-time PCR testing at CDC on May 18 confirmed that the patient was infected with the West African clade of Monkeypox virus.

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India and South Africa shoulder the greatest burden of tuberculosis (TB) and human immunodeficiency virus (HIV) infection respectively, but care retention is suboptimal. We conducted a study in Pune, India, and Matlosana, South Africa, 1) to identify the factors associated with mobile phone access and comfort of use, 2) to assess access patterns. A cross-sectional study assessed mobile phone access, and comfort; a longitudinal study assessed access patterns.

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Background: Self-collection of samples for diagnostic testing offers the advantages of patient autonomy, confidentiality and convenience. Despite data showing their feasibility and accuracy, there is a need to better understand how to implement such interventions for sexually transmitted infections (STIs). To support WHO guidelines on self-care interventions, we conducted a systematic review to investigate whether self-collection of samples should be made available as an additional approach to deliver STI testing services.

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